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ONTOLOGY REPORT - ANNOTATIONS


Term:plasma membrane phospholipid scrambling
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Accession:GO:0017121 term browser browse the term
Definition:The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).
Comment:Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.
Synonyms:exact_synonym: PL scrambling
 related_synonym: phospholipid scrambling


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plasma membrane phospholipid scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 ISO (PMID:25651887), (PMID:30700552)
(MGI:5440105|PMID:23021219)
UniProt PMID:23021219 PMID:25651887 PMID:30700552 MGI:5440105 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G LOC100688853 phospholipid scramblase 1-like IEA
IBA
(PMID:21873635) InterPro
GO_Central
Ensembl
PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr23:41,591,425...41,625,918
Ensembl chr23:41,599,843...41,669,112
JBrowse link
G LOC611500 phospholipid scramblase 1 IEA
IBA
(PMID:21873635) InterPro
GO_Central
Ensembl
PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr23:41,639,938...41,668,972
Ensembl chr23:41,599,843...41,669,112
JBrowse link
G P2RX7 purinergic receptor P2X 7 IEA Ensembl GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G PLSCR3 phospholipid scramblase 3 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 5:32,326,798...32,332,076
Ensembl chr 5:32,327,475...32,331,401
JBrowse link
G PLSCR4 phospholipid scramblase 4 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr23:41,415,151...41,453,727
Ensembl chr23:41,415,079...41,450,001
JBrowse link
G PLSCR5 phospholipid scramblase family member 5 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr23:41,709,662...41,739,638
Ensembl chr23:41,681,017...41,733,150
JBrowse link
G SLC4A1 solute carrier family 4 member 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:19,142,884...19,159,449
Ensembl chr 9:19,146,480...19,157,915
JBrowse link
calcium activated galactosylceramide scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO3 anoctamin 3 IEA Ensembl GO_REF:0000107 NCBI chr21:47,046,020...47,416,360
Ensembl chr21:47,045,978...47,410,908
JBrowse link
G ANO4 anoctamin 4 IEA Ensembl GO_REF:0000107 NCBI chr15:39,740,496...40,149,039
Ensembl chr15:39,740,337...40,149,024
JBrowse link
G ANO6 anoctamin 6 IEA Ensembl GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G ANO7 anoctamin 7 IEA Ensembl GO_REF:0000107 NCBI chr25:51,209,628...51,226,581
Ensembl chr25:51,209,003...51,226,959
JBrowse link
G ANO9 anoctamin 9 IEA Ensembl GO_REF:0000107 NCBI chr18:25,556,356...25,570,242
Ensembl chr18:25,556,344...25,566,407
JBrowse link
calcium activated phosphatidylcholine scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO3 anoctamin 3 IEA Ensembl GO_REF:0000107 NCBI chr21:47,046,020...47,416,360
Ensembl chr21:47,045,978...47,410,908
JBrowse link
G ANO4 anoctamin 4 IEA Ensembl GO_REF:0000107 NCBI chr15:39,740,496...40,149,039
Ensembl chr15:39,740,337...40,149,024
JBrowse link
G ANO6 anoctamin 6 IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G ANO7 anoctamin 7 IEA Ensembl GO_REF:0000107 NCBI chr25:51,209,628...51,226,581
Ensembl chr25:51,209,003...51,226,959
JBrowse link
G ANO9 anoctamin 9 IEA Ensembl GO_REF:0000107 NCBI chr18:25,556,356...25,570,242
Ensembl chr18:25,556,344...25,566,407
JBrowse link
calcium activated phosphatidylserine scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO4 anoctamin 4 IEA Ensembl GO_REF:0000107 NCBI chr15:39,740,496...40,149,039
Ensembl chr15:39,740,337...40,149,024
JBrowse link
G ANO6 anoctamin 6 IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G ANO7 anoctamin 7 IEA Ensembl GO_REF:0000107 NCBI chr25:51,209,628...51,226,581
Ensembl chr25:51,209,003...51,226,959
JBrowse link
G ANO9 anoctamin 9 IEA Ensembl GO_REF:0000107 NCBI chr18:25,556,356...25,570,242
Ensembl chr18:25,556,344...25,566,407
JBrowse link
calcium activated phospholipid scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO3 anoctamin 3 IEA InterPro GO_REF:0000002 NCBI chr21:47,046,020...47,416,360
Ensembl chr21:47,045,978...47,410,908
JBrowse link
G ANO4 anoctamin 4 IEA InterPro GO_REF:0000002 NCBI chr15:39,740,496...40,149,039
Ensembl chr15:39,740,337...40,149,024
JBrowse link
G ANO6 anoctamin 6 IEA InterPro GO_REF:0000002 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G ANO7 anoctamin 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:51,209,628...51,226,581
Ensembl chr25:51,209,003...51,226,959
JBrowse link
G ANO9 anoctamin 9 IEA InterPro GO_REF:0000002 NCBI chr18:25,556,356...25,570,242
Ensembl chr18:25,556,344...25,566,407
JBrowse link
G LOC477430 protein phosphatase 1 regulatory subunit 7-like IBA (PMID:21873635) GO_Central PMID:21873635
phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 NOT ISO (MGI:5486117|PMID:22936354)
(MGI:5496475|PMID:23532839)
MGI PMID:22936354 PMID:23532839 MGI:5486117 MGI:5496475 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G LOC611500 phospholipid scramblase 1 ISO (PMID:32110987)
(MGI:6450314|PMID:32110987)
(MGI:5284813|PMID:12509439)
UniProt
MGI
PMID:12509439 PMID:32110987 MGI:5284813 MGI:6450314 NCBI chr23:41,639,938...41,668,972
Ensembl chr23:41,599,843...41,669,112
JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 ISO (MGI:6450314|PMID:32110987) UniProt PMID:32110987 MGI:6450314 NCBI chr  X:84,835,130...84,989,609
Ensembl chr  X:84,801,096...85,116,625
JBrowse link
G XKR4 XK related 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:6,640,108...7,081,182
Ensembl chr29:6,640,108...7,064,029
JBrowse link
G XKR5 XK related 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:58,836,581...58,861,698
Ensembl chr16:58,841,135...58,852,668
JBrowse link
G XKR7 XK related 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:21,403,557...21,432,207
Ensembl chr24:21,403,557...21,426,295
JBrowse link
G XKR8 XK related 8 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:72,419,950...72,426,315
Ensembl chr 2:72,418,872...72,450,737
JBrowse link
G XKR9 XK related 9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:19,709,517...19,794,811
Ensembl chr29:19,753,291...19,794,747
JBrowse link
phosphatidylserine exposure on blood platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 IEA Ensembl GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16186
    cellular process 15465
      cellular component organization or biogenesis 6053
        cellular component organization 5885
          membrane organization 711
            plasma membrane organization 116
              plasma membrane phospholipid scrambling 19
                calcium activated phospholipid scrambling + 6
                phosphatidylserine exposure on apoptotic cell surface + 8
                phosphatidylserine exposure on blood platelet 1
                phosphatidylserine exposure on osteoblast involved in bone mineralization 0
Path 2
Term Annotations click to browse term
  biological_process 16186
    localization 5960
      establishment of localization 4453
        transport 4304
          ion transport 3249
            anion transport 2475
              organic substance transport 2349
                organophosphate ester transport 143
                  phospholipid transport 88
                    phospholipid translocation 46
                      plasma membrane phospholipid scrambling 19
                        calcium activated phospholipid scrambling + 6
                        phosphatidylserine exposure on apoptotic cell surface + 8
                        phosphatidylserine exposure on blood platelet 1
                        phosphatidylserine exposure on osteoblast involved in bone mineralization 0
paths to the root