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ONTOLOGY REPORT - ANNOTATIONS


Term:plasma membrane phospholipid scrambling
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Accession:GO:0017121 term browser browse the term
Definition:The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).
Comment:Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.
Synonyms:exact_synonym: PL scrambling
 related_synonym: phospholipid scrambling


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plasma membrane phospholipid scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 ISS
IMP
(PMID:25651887), (PMID:30700552) UniProtKB
UniProt
PMID:25651887 PMID:30700552 GO_REF:0000024 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G P2RX7 purinergic receptor P2X 7 IDA (PMID:25651887) UniProtKB PMID:25651887 NCBI chr12:121,132,819...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G PLSCR1 phospholipid scramblase 1 IDA
IBA
IEA
(PMID:10770950), (PMID:18629440), (PMID:9218461)
(PMID:21873635)
UniProtKB
GO_Central
InterPro
PMID:9218461 PMID:10770950 PMID:18629440 PMID:21873635 GO_REF:0000002 NCBI chr 3:146,515,178...146,544,805
Ensembl chr 3:146,515,180...146,544,856
JBrowse link
G PLSCR2 phospholipid scramblase 2 NAS
IBA
IEA
(PMID:10930526)
(PMID:21873635)
UniProtKB
GO_Central
InterPro
PMID:10930526 PMID:21873635 GO_REF:0000002 NCBI chr 3:146,391,363...146,497,163
Ensembl chr 3:146,391,421...146,495,991
JBrowse link
G PLSCR3 phospholipid scramblase 3 NAS
IBA
IEA
(PMID:10930526)
(PMID:21873635)
UniProtKB
GO_Central
InterPro
PMID:10930526 PMID:21873635 GO_REF:0000002 NCBI chr17:7,389,727...7,394,525
Ensembl chr17:7,389,727...7,394,842
JBrowse link
G PLSCR4 phospholipid scramblase 4 NAS
IBA
IEA
(PMID:10930526)
(PMID:21873635)
UniProtKB
GO_Central
InterPro
PMID:10930526 PMID:21873635 GO_REF:0000002 NCBI chr 3:146,192,335...146,251,125
Ensembl chr 3:146,192,335...146,251,179
JBrowse link
G PLSCR5 phospholipid scramblase family member 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:146,576,555...146,605,427
Ensembl chr 3:146,576,555...146,606,216
JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) IEA Ensembl GO_REF:0000107 NCBI chr17:44,248,390...44,268,161
Ensembl chr17:44,248,390...44,268,141
JBrowse link
calcium activated galactosylceramide scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO3 anoctamin 3 IEA Ensembl GO_REF:0000107 NCBI chr11:26,188,808...26,667,907
Ensembl chr11:26,188,842...26,663,289
JBrowse link
G ANO4 anoctamin 4 IEA Ensembl GO_REF:0000107 NCBI chr12:100,717,457...101,128,641
Ensembl chr12:100,717,526...101,128,641
JBrowse link
G ANO6 anoctamin 6 IEA Ensembl GO_REF:0000107 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G ANO7 anoctamin 7 IEA Ensembl GO_REF:0000107 NCBI chr 2:241,188,551...241,239,602
Ensembl chr 2:241,188,509...241,225,377
JBrowse link
G ANO9 anoctamin 9 IEA Ensembl GO_REF:0000107 NCBI chr11:417,934...442,011
Ensembl chr11:417,933...442,011
JBrowse link
calcium activated phosphatidylcholine scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO3 anoctamin 3 IEA Ensembl GO_REF:0000107 NCBI chr11:26,188,808...26,667,907
Ensembl chr11:26,188,842...26,663,289
JBrowse link
G ANO4 anoctamin 4 IEA Ensembl GO_REF:0000107 NCBI chr12:100,717,457...101,128,641
Ensembl chr12:100,717,526...101,128,641
JBrowse link
G ANO6 anoctamin 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G ANO7 anoctamin 7 IEA Ensembl GO_REF:0000107 NCBI chr 2:241,188,551...241,239,602
Ensembl chr 2:241,188,509...241,225,377
JBrowse link
G ANO9 anoctamin 9 IEA Ensembl GO_REF:0000107 NCBI chr11:417,934...442,011
Ensembl chr11:417,933...442,011
JBrowse link
calcium activated phosphatidylserine scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO4 anoctamin 4 IEA Ensembl GO_REF:0000107 NCBI chr12:100,717,457...101,128,641
Ensembl chr12:100,717,526...101,128,641
JBrowse link
G ANO6 anoctamin 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G ANO7 anoctamin 7 IEA Ensembl GO_REF:0000107 NCBI chr 2:241,188,551...241,239,602
Ensembl chr 2:241,188,509...241,225,377
JBrowse link
G ANO9 anoctamin 9 IEA Ensembl GO_REF:0000107 NCBI chr11:417,934...442,011
Ensembl chr11:417,933...442,011
JBrowse link
calcium activated phospholipid scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO3 anoctamin 3 IEA InterPro GO_REF:0000002 NCBI chr11:26,188,808...26,667,907
Ensembl chr11:26,188,842...26,663,289
JBrowse link
G ANO4 anoctamin 4 IEA InterPro GO_REF:0000002 NCBI chr12:100,717,457...101,128,641
Ensembl chr12:100,717,526...101,128,641
JBrowse link
G ANO6 anoctamin 6 ISO (MGI:5486117|PMID:22936354)
(MGI:5496475|PMID:23532839)
MGI PMID:22936354 PMID:23532839 MGI:5486117 MGI:5496475 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G ANO7 anoctamin 7 IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 2:241,188,551...241,239,602
Ensembl chr 2:241,188,509...241,225,377
JBrowse link
phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 NOT ISO (MGI:5496475|PMID:23532839)
(MGI:5486117|PMID:22936354)
MGI PMID:22936354 PMID:23532839 MGI:5486117 MGI:5496475 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link
G PLSCR1 phospholipid scramblase 1 IMP (PMID:32110987) UniProt PMID:32110987 NCBI chr 3:146,515,178...146,544,805
Ensembl chr 3:146,515,180...146,544,856
JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 ISS UniProt GO_REF:0000024 NCBI chr  X:111,768,011...112,082,943
Ensembl chr  X:111,774,315...112,082,776
JBrowse link
G XKR4 XK related 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:55,102,028...55,542,054
Ensembl chr 8:55,102,028...55,542,054
JBrowse link
G XKR5 XK related 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:6,808,517...6,835,524
Ensembl chr 8:6,808,517...6,835,524
JBrowse link
G XKR6 XK related 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:10,893,764...11,201,833
Ensembl chr 8:10,896,045...11,201,833
JBrowse link
G XKR7 XK related 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:31,968,151...32,003,387
Ensembl chr20:31,968,151...32,003,387
JBrowse link
G XKR8 XK related 8 IDA
IBA
(PMID:23845944)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635 PMID:23845944 NCBI chr 1:27,959,557...27,968,093
Ensembl chr 1:27,959,588...27,968,093
Ensembl chr 1:27,959,588...27,968,093
Ensembl chr 1:27,959,588...27,968,093
JBrowse link
G XKR9 XK related 9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:70,669,339...71,066,635
Ensembl chr 8:70,669,339...70,790,371
JBrowse link
phosphatidylserine exposure on blood platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 IMP (PMID:21107324) UniProtKB PMID:21107324 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,440,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18673
    cellular process 17693
      cellular component organization or biogenesis 7150
        cellular component organization 6960
          membrane organization 1025
            plasma membrane organization 118
              plasma membrane phospholipid scrambling 19
                calcium activated phospholipid scrambling + 5
                phosphatidylserine exposure on apoptotic cell surface + 9
                phosphatidylserine exposure on blood platelet 1
                phosphatidylserine exposure on osteoblast involved in bone mineralization 0
Path 2
Term Annotations click to browse term
  biological_process 18673
    localization 7210
      establishment of localization 5658
        transport 5517
          ion transport 3882
            anion transport 3090
              organic substance transport 2964
                organophosphate ester transport 150
                  phospholipid transport 95
                    phospholipid translocation 46
                      plasma membrane phospholipid scrambling 19
                        calcium activated phospholipid scrambling + 5
                        phosphatidylserine exposure on apoptotic cell surface + 9
                        phosphatidylserine exposure on blood platelet 1
                        phosphatidylserine exposure on osteoblast involved in bone mineralization 0
paths to the root