Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-diphthamide biosynthetic process from peptidyl-histidine
go back to main search page
Accession:GO:0017183 term browser browse the term
Definition:The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
Synonyms:exact_synonym: peptidyl-diphthamide anabolism from peptidyl-histidine;   peptidyl-diphthamide formation from peptidyl-histidine;   peptidyl-diphthamide synthesis from peptidyl-histidine
 xref: RESID:AA0040


show annotations for term's descendants       view all columns           Sort by:
 
peptidyl-diphthamide biosynthetic process from peptidyl-histidine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dph1 diphthamide biosynthesis 1 JBrowse link 10 62,019,379 62,032,384 RGD:1600115
RGD:13792537
G Dph2 diphthamide biosynthesis 2 JBrowse link 5 136,723,398 136,726,358 RGD:1600115
RGD:13792537
G Dph3 diphthamide biosynthesis 3 JBrowse link 16 8,202,048 8,207,492 RGD:13792537
G Dph5 diphthamide biosynthesis 5 JBrowse link 2 218,834,034 218,866,763 RGD:13792537
G Dph6 diphthamine biosynthesis 6 JBrowse link 3 106,007,721 106,136,662 RGD:1600115
RGD:13792537
G Dph7 diphthamide biosynthesis 7 JBrowse link 3 2,170,193 2,179,101 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      biosynthetic process 5989
        cellular biosynthetic process 5814
          peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      cellular metabolic process 10644
        cellular nitrogen compound metabolic process 6382
          cellular amide metabolic process 1394
            amide biosynthetic process 1121
              peptide biosynthetic process 1001
                translation 982
                  regulation of translation 357
                    regulation of cytoplasmic translation 26
                      regulation of cytoplasmic translational elongation 8
                        peptidyl-diphthamide biosynthetic process from peptidyl-histidine 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.