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ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-lysine trimethylation
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Accession:GO:0018023 term browser browse the term
Definition:The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
Synonyms:xref: RESID:AA0074


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peptidyl-lysine trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Antkmt adenine nucleotide translocase lysine methyltransferase JBrowse link 10 15,160,037 15,161,895 RGD:1624291
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase JBrowse link 2 84,678,892 84,694,152 RGD:1600115
RGD:1624291
G Eef2kmt eukaryotic elongation factor 2 lysine methyltransferase JBrowse link 10 10,530,302 10,540,428 RGD:1624291
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase JBrowse link 4 183,655,968 183,665,757 RGD:1624291
RGD:1600115
G LOC100910833 histone-lysine N-methyltransferase setd3-like JBrowse link 6 131,602,149 131,650,424 RGD:13792537
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
G Setd3 SET domain containing 3, actin histidine methyltransferase JBrowse link 6 132,023,128 132,090,072 RGD:13792537
RGD:1624291
G Vcpkmt valosin containing protein lysine methyltransferase JBrowse link 6 91,880,342 91,884,336 RGD:1624291
histone H3-K36 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1600115
RGD:1624291
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
G Setd5 SET domain containing 5 JBrowse link 4 145,017,549 145,095,247 RGD:1624291
histone H3-K4 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid4a AT-rich interaction domain 4A JBrowse link 6 93,461,713 93,532,901 RGD:1624291
G Bend3 BEN domain containing 3 JBrowse link 20 48,248,193 48,270,905 RGD:1624291
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 175,839,140 175,869,167 RGD:1624291
G H1f2 H1.2 linker histone, cluster member JBrowse link 17 43,638,938 43,640,445 RGD:1624291
G H1f4 H1.4 linker histone, cluster member JBrowse link 17 43,734,461 43,735,120 RGD:1624291
G H4f3 H1.3 linker histone, cluster member JBrowse link 17 43,797,711 43,798,450 RGD:1624291
G Kmt2a lysine methyltransferase 2A JBrowse link 8 49,110,407 49,185,872 RGD:1624291
G Kmt2b lysine methyltransferase 2B JBrowse link 1 89,022,889 89,042,176 RGD:1624291
G Kmt2d lysine methyltransferase 2D JBrowse link 7 140,507,137 140,542,479 RGD:1624291
G Ncoa6 nuclear receptor coactivator 6 JBrowse link 3 150,919,317 150,990,391 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1624291
RGD:1600115
G Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) JBrowse link 3 111,478,350 111,537,941 RGD:1624291
G Setd1a SET domain containing 1A, histone lysine methyltransferase JBrowse link 1 199,222,584 199,247,993 RGD:1624291
G Setd1b SET domain containing 1B, histone lysine methyltransferase JBrowse link 12 38,843,167 38,869,180 RGD:1600115
RGD:1624291
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 2 238,719,389 238,802,975 RGD:1624291
G Tet3 tet methylcytosine dioxygenase 3 JBrowse link 4 115,060,702 115,160,800 RGD:1624291
G Wdr61 WD repeat domain 61 JBrowse link 8 59,296,339 59,313,663 RGD:1624291
RGD:1600115
G Wdr82 WD repeat domain 82 JBrowse link 8 114,866,769 114,886,208 RGD:13792537
G Zfp335 zinc finger protein 335 JBrowse link 3 161,357,201 161,378,073 RGD:1600115
RGD:13792537
RGD:1624291
histone H3-K9 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid4a AT-rich interaction domain 4A JBrowse link 6 93,461,713 93,532,901 RGD:1624291
G Arid4b AT-rich interaction domain 4B JBrowse link 17 53,831,353 53,955,897 RGD:1624291
G Bend3 BEN domain containing 3 JBrowse link 20 48,248,193 48,270,905 RGD:1624291
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 JBrowse link 2 196,495,867 196,527,412 RGD:1624291
G Suv39h1 suppressor of variegation 3-9 homolog 1 JBrowse link X 146,532,002 146,533,538 RGD:1624291
G Suv39h2 suppressor of variegation 3-9 homolog 2 JBrowse link 17 78,762,897 78,782,016 RGD:1624291
histone H4-K20 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid4a AT-rich interaction domain 4A JBrowse link 6 93,461,713 93,532,901 RGD:1624291
G Arid4b AT-rich interaction domain 4B JBrowse link 17 53,831,353 53,955,897 RGD:1624291
G Bend3 BEN domain containing 3 JBrowse link 20 48,248,193 48,270,905 RGD:1624291
G Kmt5b lysine methyltransferase 5B JBrowse link 1 219,000,844 219,050,211 RGD:13792537
G Kmt5c lysine methyltransferase 5C JBrowse link 1 72,666,662 72,674,271 RGD:1624291
RGD:13792537
G Pwp1 PWP1 homolog, endonuclein JBrowse link 7 23,988,776 24,004,774 RGD:1624291
negative regulation of histone H3-K9 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm4a lysine demethylase 4A JBrowse link 5 136,967,650 137,014,402 RGD:1624291
G Kdm4b lysine demethylase 4B JBrowse link 9 10,656,035 10,734,127 RGD:1624291
G Kdm4c lysine demethylase 4C JBrowse link 5 90,800,139 91,012,662 RGD:1624291
G Kdm4d lysine demethylase 4D JBrowse link 8 12,968,192 12,993,651 RGD:1624291
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 JBrowse link 20 13,679,955 13,702,821 RGD:1624291
positive regulation of histone H3-K36 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brd4 bromodomain containing 4 JBrowse link 7 14,222,101 14,303,055 RGD:1624291
G Nsd3 nuclear receptor binding SET domain protein 3 JBrowse link 16 71,126,276 71,237,118 RGD:1624291
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1624291
RGD:1600115
positive regulation of histone H3-K4 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kmt2e lysine methyltransferase 2E JBrowse link 4 8,187,751 8,255,578 RGD:1624291
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1600115
RGD:1624291
positive regulation of histone H3-K9 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmrtc2 DMRT-like family C2 JBrowse link 1 81,734,256 81,741,419 RGD:1624291
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:1624291
RGD:1600115
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1600115
RGD:1624291
G Suv39h1 suppressor of variegation 3-9 homolog 1 JBrowse link X 146,532,002 146,533,538 RGD:1624291
regulation of histone H3-K36 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Iws1 interacts with SUPT6H, CTD assembly factor 1 JBrowse link 18 24,849,508 24,891,339 RGD:1600115
RGD:13792537
RGD:1624291
regulation of histone H3-K9 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:1600115
RGD:1624291
G Zfp110 zinc finger protein 110 JBrowse link 1 65,741,769 65,757,709 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      methylation 359
        macromolecule methylation 328
          protein methylation 202
            peptidyl-lysine methylation 139
              peptidyl-lysine trimethylation 52
                histone H3-K36 trimethylation + 6
                histone H3-K4 trimethylation + 21
                histone H3-K9 trimethylation + 18
                histone H4-K20 trimethylation 6
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      organic substance metabolic process 11297
        organonitrogen compound metabolic process 6969
          protein metabolic process 6070
            protein modification process 3882
              cellular protein modification process 3882
                peptidyl-amino acid modification 1289
                  peptidyl-lysine modification 397
                    peptidyl-lysine methylation 139
                      peptidyl-lysine trimethylation 52
                        histone H3-K36 trimethylation + 6
                        histone H3-K4 trimethylation + 21
                        histone H3-K9 trimethylation + 18
                        histone H4-K20 trimethylation 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.