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Term:peptidyl-lysine oxidation
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Accession:GO:0018057 term browser browse the term
Definition:The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.
Synonyms:xref: RESID:AA0121

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peptidyl-lysine oxidation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lox lysyl oxidase JBrowse link NW_004955521 178,290 193,926 RGD:9068941
G Loxl1 lysyl oxidase like 1 JBrowse link NW_004955450 3,715,109 3,734,641 RGD:9068941
G Loxl2 lysyl oxidase like 2 JBrowse link NW_004955403 46,503,226 46,583,807 RGD:9068941
G Loxl3 lysyl oxidase like 3 JBrowse link NW_004955424 11,236,415 11,255,801 RGD:9068941
G Loxl4 lysyl oxidase like 4 JBrowse link NW_004955507 4,229,284 4,260,005 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14616
    metabolic process 10124
      oxidation-reduction process 901
        protein oxidation 14
          peptidyl-lysine oxidation 5
Path 2
Term Annotations click to browse term
  biological_process 14616
    metabolic process 10124
      organic substance metabolic process 9625
        macromolecule metabolic process 8332
          cellular macromolecule metabolic process 7276
            cellular protein metabolic process 4786
              cellular protein modification process 3845
                peptidyl-amino acid modification 1194
                  peptidyl-lysine modification 378
                    peptidyl-lysine oxidation 5
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.