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ONTOLOGY REPORT - ANNOTATIONS


Term:peptide cross-linking via lanthionine or 3-methyl-lanthionine
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Accession:GO:0018081 term browser browse the term
Definition:The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process.
Synonyms:exact_synonym: peptide cross-linking via the thioethers lanthionine or 3-methyl-lanthionine;   peptide cross-linking via the thiolethers lanthionine or 3-methyl-lanthionine
 xref: RESID:AA0110;   RESID:AA0111;   RESID:AA0112


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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      cellular metabolic process 10566
        cellular macromolecule metabolic process 8127
          cellular protein metabolic process 5293
            cellular protein modification process 3851
              peptide cross-linking 34
                peptide cross-linking via lanthionine or 3-methyl-lanthionine 0
                  peptide cross-linking via (2R,6R)-lanthionine 0
                  peptide cross-linking via sn-(2S,6R)-lanthionine 0
Path 2
Term Annotations click to browse term
  biological_process 19332
    metabolic process 11554
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          protein metabolic process 5973
            protein modification process 3851
              cellular protein modification process 3851
                peptide cross-linking 34
                  peptide cross-linking via lanthionine or 3-methyl-lanthionine 0
                    peptide cross-linking via (2R,6R)-lanthionine 0
                    peptide cross-linking via sn-(2S,6R)-lanthionine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.