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ONTOLOGY REPORT - ANNOTATIONS


Term:protein hydroxylation
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Accession:GO:0018126 term browser browse the term
Definition:The addition of a hydroxy group to a protein amino acid.
Synonyms:exact_synonym: protein amino acid hydroxylation


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protein hydroxylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO (PMID:19584355) RGD PMID:19584355 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Jmjd4 jumonji domain containing 4 ISO (PMID:24486019) RGD PMID:24486019 NCBI chr10:45,798,964...45,804,188
Ensembl chr10:45,798,797...45,804,541
JBrowse link
G Jmjd7 jumonji domain containing 7 ISO (PMID:29915238) RGD PMID:29915238 NCBI chr 3:111,818,150...111,824,211
Ensembl chr 3:111,818,150...111,824,211
JBrowse link
G Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 ISO (PMID:24550447), (PMID:24550462) RGD PMID:24550447, PMID:24550462 NCBI chr19:11,425,301...11,451,085
Ensembl chr19:11,425,105...11,451,278
JBrowse link
G P3h1 prolyl 3-hydroxylase 1 ISO (PMID:17277775) RGD PMID:17277775 NCBI chr 5:138,279,597...138,294,280
Ensembl chr 5:138,279,506...138,294,262
JBrowse link
G Pah phenylalanine hydroxylase IDA RGD PMID:16953590 RGD:1601531 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
peptidyl-asparagine hydroxylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor ISO
IBA
(PMID:12080085), (PMID:12215170), (PMID:14734545), (PMID:19245366), (PMID:21177872)
PMID:21873635
RGD PMID:12080085, PMID:12215170, PMID:14734545, PMID:19245366, PMID:21177872, PMID:21873635 RGD:13792537 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
peptidyl-aspartic acid hydroxylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase IBA
ISO
PMID:21873635
(MGI:2177999|PMID:11773073)
RGD PMID:11773073, PMID:21873635 MGI:2177999, RGD:13792537 NCBI chr 5:22,577,680...22,799,333
Ensembl chr 5:22,577,675...22,799,349
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor ISO
IBA
(PMID:21177872)
PMID:21873635
RGD PMID:21177872, PMID:21873635 RGD:13792537 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
peptidyl-histidine hydroxylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor ISO
IBA
(PMID:21251231)
PMID:21873635
RGD PMID:21251231, PMID:21873635 RGD:13792537 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
peptidyl-lysine hydroxylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp10 FKBP prolyl isomerase 10 ISO MGI:5432211 (MGI:5585367|PMID:24777781), (MGI:6114458|PMID:28206698) RGD PMID:24777781, PMID:28206698 MGI:5585367, MGI:6114458 NCBI chr10:88,326,337...88,338,199
Ensembl chr10:88,326,080...88,338,207
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 ISO (MGI:5888787|PMID:28115524) RGD PMID:28115524 MGI:5888787 NCBI chr 4:157,359,331...157,375,186
Ensembl chr 4:157,359,332...157,372,861
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 ISS
ISO
IBA
GO_REF:0000024
(MGI:5779580|PMID:27119146)
PMID:21873635
UniProt
RGD
PMID:27119146, PMID:21873635 GO_REF:0000024, MGI:5779580, RGD:13792537 NCBI chr10:88,318,231...88,325,326
Ensembl chr10:88,318,817...88,325,326
JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IDA
IBA
ISO
IEA
PMID:21873635
(PMID:10934207), (PMID:8621606), (PMID:9724729)
PMID:7578263
GO_REF:0000107
RGD
Ensembl
PMID:8621606, PMID:9724729, PMID:10934207, PMID:11714250, PMID:21873635, PMID:7578263 GO_REF:0000107, RGD:1599090, RGD:13792537, RGD:734487 NCBI chr 5:164,720,629...164,747,071
Ensembl chr 5:164,720,587...164,747,083
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:10934207)
Ensembl
RGD
PMID:10934207, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISS
ISO
IBA
GO_REF:0000024
(MGI:5804716|PMID:27435297), (MGI:6202004|PMID:16447251)
(PMID:10934207), (PMID:18298658), (PMID:9582318), (PMID:9724729)
PMID:21873635
UniProt
RGD
PMID:9582318, PMID:9724729, PMID:10934207, PMID:16447251, PMID:18298658, PMID:27435297, PMID:21873635 GO_REF:0000024, MGI:5804716, MGI:6202004, RGD:13792537 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog IEA
ISO
GO_REF:0000107
MGI:3699244|MGI:5816979 (MGI:5804716|PMID:27435297)
(PMID:27435297)
Ensembl
RGD
PMID:27435297 GO_REF:0000107, MGI:5804716 NCBI chr 6:111,271,283...111,296,013
Ensembl chr 6:111,271,240...111,295,994
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated ISO (PMID:27435297)
MGI:3699244|MGI:5770088 (MGI:5804716|PMID:27435297)
RGD PMID:27435297 MGI:5804716 NCBI chr 1:142,060,955...142,083,955
Ensembl chr 1:142,060,955...142,083,953
JBrowse link
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase ISS
ISO
GO_REF:0000024
(PMID:19574390), (PMID:22189873)
UniProt
RGD
PMID:19574390, PMID:22189873 GO_REF:0000024 NCBI chr10:105,781,752...105,787,803
Ensembl chr10:105,781,753...105,787,803
JBrowse link
peptidyl-proline hydroxylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 ISO
IBA
(PMID:24550447)
PMID:21873635
RGD PMID:24550447, PMID:21873635 RGD:13792537 NCBI chr19:11,425,301...11,451,085
Ensembl chr19:11,425,105...11,451,278
JBrowse link
G P3h1 prolyl 3-hydroxylase 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:138,279,597...138,294,280
Ensembl chr 5:138,279,506...138,294,262
JBrowse link
G P3h2 prolyl 3-hydroxylase 2 IDA
ISS
ISO
IEA
PMID:21757687
GO_REF:0000024
(PMID:18487197)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18487197, PMID:21757687 GO_REF:0000024, GO_REF:0000107, RGD:8553392 NCBI chr11:78,028,885...78,169,746
Ensembl chr11:78,029,038...78,169,648
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:157,359,331...157,375,186
Ensembl chr 4:157,359,332...157,372,861
JBrowse link
G P4ha3 prolyl 4-hydroxylase subunit alpha 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:165,295,835...165,330,922
Ensembl chr 1:165,295,847...165,330,322
JBrowse link
peptidyl-proline hydroxylation to 3-hydroxy-L-proline term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtap cartilage associated protein ISO MGI:3693334 (MGI:3692844|PMID:17055431) RGD PMID:17055431 MGI:3692844 NCBI chr 8:122,382,613...122,402,209 JBrowse link
G Crtapl1 cartilage associated protein-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:122,394,451...122,402,198
Ensembl chr 8:122,417,532...122,421,384
JBrowse link
peptidyl-proline hydroxylation to 4-hydroxy-L-proline term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07004992.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:173,275,336...173,284,941 JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISO
IBA
(PMID:11598268)
PMID:21873635
RGD PMID:11598268, PMID:21873635 RGD:13792537 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 IDA
IBA
ISO
PMID:15925519
PMID:21873635
(PMID:11598268), (PMID:12039559)
RGD PMID:11598268, PMID:12039559, PMID:15925519, PMID:21873635 RGD:13602003, RGD:13792537 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO
IBA
IEA
(PMID:11598268)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:11598268, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha ISO MGI:1859815|MGI:1914725 (MGI:5461404|PMID:22981861) RGD PMID:22981861 MGI:5461404 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta ISO MGI:1354385|MGI:1859815 (MGI:5461404|PMID:22981861) RGD PMID:22981861 MGI:5461404 NCBI chr17:90,709,394...90,783,110
Ensembl chr17:90,710,555...90,756,048
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 TAS
ISO
IBA
(MGI:72931|PMID:7753822)
PMID:21873635
RGD PMID:7753822, PMID:11997102, PMID:21873635 MGI:72931, RGD:625562, RGD:13792537 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 IBA
ISO
PMID:21873635
(MGI:72931|PMID:7753822)
RGD PMID:7753822, PMID:21873635 MGI:72931, RGD:13792537 NCBI chr10:39,435,227...39,464,134
Ensembl chr10:39,435,227...39,464,188
JBrowse link
G P4ha3 prolyl 4-hydroxylase subunit alpha 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:165,295,835...165,330,922
Ensembl chr 1:165,295,847...165,330,322
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta ISO (PMID:7753822) RGD PMID:7753822 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G P4htm prolyl 4-hydroxylase, transmembrane IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:117,364,895...117,383,275
Ensembl chr 8:117,365,101...117,382,715
JBrowse link
G Prdx4 peroxiredoxin 4 ISO MGI:1354385|MGI:1914725 (MGI:5461404|PMID:22981861) RGD PMID:22981861 MGI:5461404 NCBI chr  X:43,495,453...43,512,994
Ensembl chr  X:43,497,763...43,512,991
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular macromolecule metabolic process 8548
          cellular protein metabolic process 5564
            cellular protein modification process 3948
              protein hydroxylation 31
                peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine 0
                peptidyl-asparagine hydroxylation + 1
                peptidyl-aspartic acid hydroxylation + 2
                peptidyl-histidine hydroxylation 1
                peptidyl-lysine hydroxylation + 9
                peptidyl-proline hydroxylation + 18
                peptidyl-tyrosine hydroxylation + 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        macromolecule metabolic process 10077
          protein metabolic process 6221
            protein modification process 3948
              cellular protein modification process 3948
                protein hydroxylation 31
                  peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine 0
                  peptidyl-asparagine hydroxylation + 1
                  peptidyl-aspartic acid hydroxylation + 2
                  peptidyl-histidine hydroxylation 1
                  peptidyl-lysine hydroxylation + 9
                  peptidyl-proline hydroxylation + 18
                  peptidyl-tyrosine hydroxylation + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.