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ONTOLOGY REPORT - ANNOTATIONS


Term:3-hydroxyacyl-CoA dehydratase activity
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Accession:GO:0018812 term browser browse the term
Definition:Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).
Synonyms:xref: reactome:R-HSA-8957389 "RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA"


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3-hydroxyacyl-CoA dehydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 ISO
IBA
(PMID:18554506)
PMID:21873635
RGD PMID:18554506, PMID:21873635 RGD:13792537 NCBI chr17:81,173,238...81,196,012
Ensembl chr17:81,173,713...81,187,739
JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 ISO
IBA
(PMID:18554506)
PMID:21873635
RGD PMID:18554506, PMID:21873635 RGD:13792537 NCBI chr11:68,893,684...68,985,635
Ensembl chr11:68,894,445...68,989,988
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 ISO
IBA
(PMID:18554506)
PMID:21873635
RGD PMID:18554506, PMID:21873635 RGD:13792537 NCBI chr 8:70,471,572...70,509,874
Ensembl chr 8:70,471,572...70,509,874
JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 ISO
IBA
(PMID:18554506)
PMID:21873635
RGD PMID:18554506, PMID:21873635 RGD:13792537 NCBI chr 5:106,728,401...106,758,068
Ensembl chr 5:106,732,513...106,758,032
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 IDA RGD PMID:8902630 RGD:10411904 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link

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  molecular_function 20457
    catalytic activity 6065
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            3-hydroxyacyl-CoA dehydratase activity 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.