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ONTOLOGY REPORT - ANNOTATIONS


Term:isopentenyl diphosphate biosynthetic process, mevalonate pathway
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Accession:GO:0019287 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
Synonyms:exact_synonym: Ac-MVA pathway;   acetate-mevalonate pathway;   isopentenyl diphosphate anabolism, mevalonate pathway;   isopentenyl diphosphate biosynthetic process via mevalonate;   isopentenyl diphosphate formation, mevalonate pathway;   isopentenyl diphosphate synthesis, mevalonate pathway


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isopentenyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mvd mevalonate diphosphate decarboxylase JBrowse link 19 55,258,910 55,268,933 RGD:2316852
RGD:13792537
RGD:1600115
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:2316852
RGD:13792537
RGD:1600115
G Pmvk phosphomevalonate kinase JBrowse link 2 188,784,329 188,793,890 RGD:2316852
RGD:1600115
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      organic substance metabolic process 10949
        thioester metabolic process 88
          acyl-CoA metabolic process 88
            acetyl-CoA metabolic process 37
              isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    metabolic process 11555
      cellular metabolic process 10567
        cellular aromatic compound metabolic process 5482
          nucleobase-containing compound metabolic process 5256
            nucleobase-containing small molecule metabolic process 575
              nucleoside phosphate metabolic process 496
                nucleotide metabolic process 489
                  purine nucleotide metabolic process 402
                    purine ribonucleotide metabolic process 377
                      acyl-CoA metabolic process 88
                        acetyl-CoA metabolic process 37
                          isopentenyl diphosphate biosynthetic process, mevalonate pathway 3
                            isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process 0
                            negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                            regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.