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ONTOLOGY REPORT - ANNOTATIONS


Term:hexose catabolic process
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Accession:GO:0019320 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
Synonyms:exact_synonym: hexose breakdown;   hexose catabolism;   hexose degradation


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canonical glycolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADPGK ADP dependent glucokinase TAS Reactome Reactome:R-HSA-70171 NCBI chr15:72,751,294...72,783,776
Ensembl chr15:72,751,369...72,785,846
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A TAS Reactome Reactome:R-HSA-70171 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G ALDOB aldolase, fructose-bisphosphate B TAS Reactome Reactome:R-HSA-70171 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C TAS Reactome Reactome:R-HSA-70171 NCBI chr17:28,573,115...28,576,963
Ensembl chr17:28,573,115...28,576,948
JBrowse link
G BPGM bisphosphoglycerate mutase TAS Reactome Reactome:R-HSA-70171 NCBI chr 7:134,646,853...134,679,816
Ensembl chr 7:134,646,811...134,679,816
JBrowse link
G ENO1 enolase 1 TAS
IDA
IMP
(PMID:29775581)
(PMID:3529090)
Reactome
UniProt
CAFA
PMID:3529090, PMID:29775581 Reactome:R-HSA-70171 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ENO2 enolase 2 TAS Reactome Reactome:R-HSA-70171 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
JBrowse link
G ENO3 enolase 3 TAS Reactome Reactome:R-HSA-70171 NCBI chr17:4,949,182...4,957,131
Ensembl chr17:4,948,092...4,957,131
JBrowse link
G FOXK1 forkhead box K1 IDA (PMID:30700909) UniProt PMID:30700909 NCBI chr 7:4,682,295...4,771,442
Ensembl chr 7:4,682,295...4,771,442
JBrowse link
G FOXK2 forkhead box K2 ISS UniProt GO_REF:0000024 NCBI chr17:82,519,732...82,604,602
Ensembl chr17:82,519,713...82,644,662
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase TAS Reactome Reactome:R-HSA-70171 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic TAS Reactome Reactome:R-HSA-70171 NCBI chr19:35,533,456...35,545,319
Ensembl chr19:35,533,455...35,545,319
JBrowse link
G GCK glucokinase TAS Reactome Reactome:R-HSA-70171 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
JBrowse link
G GPI glucose-6-phosphate isomerase TAS Reactome Reactome:R-HSA-70171 NCBI chr19:34,353,330...34,402,413
Ensembl chr19:34,359,480...34,402,413
JBrowse link
G HK1 hexokinase 1 TAS Reactome Reactome:R-HSA-70171 NCBI chr10:69,269,991...69,401,882
Ensembl chr10:69,269,984...69,401,884
JBrowse link
G HK2 hexokinase 2 TAS Reactome Reactome:R-HSA-70171 NCBI chr 2:74,834,126...74,893,359
Ensembl chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
JBrowse link
G HK3 hexokinase 3 TAS Reactome Reactome:R-HSA-70171 NCBI chr 5:176,880,869...176,899,373
Ensembl chr 5:176,880,869...176,899,346
JBrowse link
G PFKL phosphofructokinase, liver type TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-70171 NCBI chr21:44,300,040...44,327,373
Ensembl chr21:44,300,051...44,327,376
JBrowse link
G PFKM phosphofructokinase, muscle TAS
IEA
IBA
(PMID:21873635) Reactome
Ensembl
GO_Central
PMID:21873635 GO_REF:0000107, Reactome:R-HSA-70171 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404
JBrowse link
G PFKP phosphofructokinase, platelet TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-70171 NCBI chr10:3,067,475...3,136,805
Ensembl chr10:3,066,333...3,137,718
JBrowse link
G PGAM1 phosphoglycerate mutase 1 TAS Reactome Reactome:R-HSA-70171 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444
JBrowse link
G PGAM2 phosphoglycerate mutase 2 TAS Reactome Reactome:R-HSA-70171 NCBI chr 7:44,062,727...44,065,567
Ensembl chr 7:44,062,727...44,065,567
JBrowse link
G PGK1 phosphoglycerate kinase 1 TAS Reactome Reactome:R-HSA-70171 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295
JBrowse link
G PGM2L1 phosphoglucomutase 2 like 1 TAS Reactome Reactome:R-HSA-70171 NCBI chr11:74,330,316...74,398,751
Ensembl chr11:74,330,316...74,398,433
JBrowse link
G PKLR pyruvate kinase L/R TAS Reactome Reactome:R-HSA-70171 NCBI chr 1:155,289,293...155,301,438
Ensembl chr 1:155,289,293...155,301,438
JBrowse link
G PKM pyruvate kinase M1/2 TAS Reactome Reactome:R-HSA-70171 NCBI chr15:72,199,029...72,231,389
Ensembl chr15:72,199,029...72,231,822
JBrowse link
G TPI1 triosephosphate isomerase 1 TAS Reactome Reactome:R-HSA-70171 NCBI chr12:6,866,834...6,870,948
Ensembl chr12:6,867,119...6,870,948
JBrowse link
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 TAS Reactome Reactome:R-HSA-70350 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDOB aldolase, fructose-bisphosphate B TAS Reactome Reactome:R-HSA-70350 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
JBrowse link
G GLYCTK glycerate kinase TAS Reactome Reactome:R-HSA-70350 NCBI chr 3:52,287,558...52,295,257
Ensembl chr 3:52,287,089...52,295,257
JBrowse link
G KHK ketohexokinase TAS Reactome Reactome:R-HSA-70350 NCBI chr 2:27,086,760...27,100,762
Ensembl chr 2:27,086,747...27,100,762
JBrowse link
G TKFC triokinase and FMN cyclase TAS Reactome Reactome:R-HSA-70350 NCBI chr11:61,333,228...61,353,426
Ensembl chr11:61,333,210...61,353,295
JBrowse link
galactose catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase TAS
IDA
(PMID:16302980) Reactome
UniProtKB
PMID:16302980 Reactome:R-HSA-70370 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781
JBrowse link
G GALK1 galactokinase 1 TAS Reactome Reactome:R-HSA-70370 NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
JBrowse link
G GALT galactose-1-phosphate uridylyltransferase TAS Reactome Reactome:R-HSA-70370 NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
JBrowse link
G GLB1 galactosidase beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:32,996,617...33,097,146
Ensembl chr 3:32,996,609...33,097,202
JBrowse link
G PGM1 phosphoglucomutase 1 TAS Reactome Reactome:R-HSA-70370 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
JBrowse link
G PGM2 phosphoglucomutase 2 TAS Reactome Reactome:R-HSA-70370 NCBI chr 4:37,826,686...37,862,937
Ensembl chr 4:37,826,660...37,862,937
JBrowse link
G PGM2L1 phosphoglucomutase 2 like 1 TAS Reactome Reactome:R-HSA-70370 NCBI chr11:74,330,316...74,398,751
Ensembl chr11:74,330,316...74,398,433
JBrowse link
galactose catabolic process via UDP-galactose term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL162231.3 novel protein (GALT-IL11RA readthrough) IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr 9:34,646,645...34,657,113 JBrowse link
G GALE UDP-galactose-4-epimerase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781
JBrowse link
G GALM galactose mutarotase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:38,665,922...38,734,765
Ensembl chr 2:38,666,081...38,741,237
JBrowse link
G GALT galactose-1-phosphate uridylyltransferase IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
JBrowse link
glucose catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death IEA Ensembl GO_REF:0000107 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G LRP5 LDL receptor related protein 5 IMP (PMID:19673927) BHF-UCL PMID:19673927 NCBI chr11:68,298,866...68,449,275
Ensembl chr11:68,312,591...68,449,275
JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:207,053,063...207,081,027
Ensembl chr 1:207,034,366...207,081,024
JBrowse link
G PFKL phosphofructokinase, liver type IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:44,300,040...44,327,373
Ensembl chr21:44,300,051...44,327,376
JBrowse link
G PFKM phosphofructokinase, muscle IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404
JBrowse link
G PFKP phosphofructokinase, platelet IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:3,067,475...3,136,805
Ensembl chr10:3,066,333...3,137,718
JBrowse link
G TKTL1 transketolase like 1 TAS (PMID:8838793) PINC PMID:8838793 NCBI chr  X:154,295,795...154,330,350
Ensembl chr  X:154,295,795...154,330,350
JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDHA lactate dehydrogenase A ISO (MGI:MGI:62497|PMID:8224816) MGI PMID:8224816 MGI:MGI:62497 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
JBrowse link
glycolytic process from galactose term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALK1 galactokinase 1 IEA Ensembl GO_REF:0000107 NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
JBrowse link
G GALT galactose-1-phosphate uridylyltransferase ISO (MGI:MGI:2180189|PMID:11286504) MGI PMID:11286504 MGI:MGI:2180189 NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
JBrowse link
L-fucose catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FUT1 fucosyltransferase 1 (H blood group) NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr19:48,748,011...48,755,358
Ensembl chr19:48,748,011...48,755,390
JBrowse link
G FUT10 fucosyltransferase 10 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr 8:33,308,102...33,473,146
Ensembl chr 8:33,370,824...33,473,146
JBrowse link
G FUT2 fucosyltransferase 2 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr19:48,695,971...48,705,951
Ensembl chr19:48,695,971...48,705,951
JBrowse link
G FUT4 fucosyltransferase 4 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr11:94,543,851...94,549,898
Ensembl chr11:94,543,840...94,549,898
JBrowse link
G FUT5 fucosyltransferase 5 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr19:5,865,826...5,870,540
Ensembl chr19:5,865,826...5,870,540
JBrowse link
G FUT6 fucosyltransferase 6 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr19:5,830,408...5,840,019
Ensembl chr19:5,830,408...5,839,722
Ensembl chr19:5,830,408...5,839,722
JBrowse link
G FUT7 fucosyltransferase 7 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr 9:137,030,174...137,032,088
Ensembl chr 9:137,030,174...137,032,088
Ensembl chr 9:137,030,174...137,032,088
JBrowse link
G FUT8 fucosyltransferase 8 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr14:65,410,592...65,744,122
Ensembl chr14:65,410,592...65,744,121
JBrowse link
G FUT9 fucosyltransferase 9 NAS (PMID:11698403) UniProtKB PMID:11698403 NCBI chr 6:96,015,974...96,215,612
Ensembl chr 6:96,015,974...96,215,612
JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A12 solute carrier family 25 member 12 IEA Ensembl GO_REF:0000107 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase IEA Ensembl GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 IEA
ISS
Ensembl
UniProtKB
GO_REF:0000024, GO_REF:0000107 NCBI chr11:66,546,395...66,563,334
Ensembl chr11:66,546,395...66,563,334
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      small molecule metabolic process 2146
        monosaccharide metabolic process 328
          monosaccharide catabolic process 67
            hexose catabolic process 57
              allose catabolic process + 0
              fructose catabolic process + 5
              fucose catabolic process + 9
              galactose catabolic process + 9
              glucose catabolic process + 36
              hexose catabolic process to acetate 0
              hexose catabolic process to acetone 0
              hexose catabolic process to butan-1-ol 0
              hexose catabolic process to butyrate + 0
              hexose catabolic process to ethanol + 0
              hexose catabolic process to propan-2-ol 0
              mannose catabolic process + 0
              rhamnose catabolic process + 0
              sorbose catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      primary metabolic process 11011
        carbohydrate metabolic process 703
          monosaccharide metabolic process 328
            hexose metabolic process 282
              hexose catabolic process 57
                allose catabolic process + 0
                fructose catabolic process + 5
                fucose catabolic process + 9
                galactose catabolic process + 9
                glucose catabolic process + 36
                hexose catabolic process to acetate 0
                hexose catabolic process to acetone 0
                hexose catabolic process to butan-1-ol 0
                hexose catabolic process to butyrate + 0
                hexose catabolic process to ethanol + 0
                hexose catabolic process to propan-2-ol 0
                mannose catabolic process + 0
                rhamnose catabolic process + 0
                sorbose catabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.