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ONTOLOGY REPORT - ANNOTATIONS


Term:trypanothione biosynthetic process
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Accession:GO:0019342 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.
Synonyms:exact_synonym: trypanothione anabolism;   trypanothione biosynthesis;   trypanothione formation;   trypanothione synthesis
 xref: MetaCyc:TRYPANOSYN-PWY


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  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        sulfur compound metabolic process 310
          glutathione derivative metabolic process 4
            trypanothione metabolic process 0
              trypanothione biosynthetic process 0
                negative regulation of trypanothione biosynthetic process 0
                positive regulation of trypanothione biosynthetic process 0
                regulation of trypanothione biosynthetic process + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.