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ONTOLOGY REPORT - ANNOTATIONS


Term:4-hydroxyproline metabolic process
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Accession:GO:0019471 term browser browse the term
Definition:The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.
Synonyms:exact_synonym: 4-hydroxyproline metabolism


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4-hydroxyproline catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 ISO (PMID:21998747) RGD PMID:21998747 NCBI chr 1:261,291,742...261,319,743
Ensembl chr 1:261,291,870...261,318,984
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Path 1
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  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular modified amino acid metabolic process 187
          4-hydroxyproline metabolic process 1
            4-hydroxyproline biosynthetic process 0
            4-hydroxyproline catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular metabolic process 11065
        organic acid metabolic process 1090
          oxoacid metabolic process 1061
            carboxylic acid metabolic process 1005
              cellular amino acid metabolic process 274
                alpha-amino acid metabolic process 198
                  4-hydroxyproline metabolic process 1
                    4-hydroxyproline biosynthetic process 0
                    4-hydroxyproline catabolic process 1
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