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ONTOLOGY REPORT - ANNOTATIONS


Term:glucose catabolic process to lactate via pyruvate
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Accession:GO:0019661 term browser browse the term
Definition:The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).
Synonyms:exact_synonym: glucose fermentation to lactate via pyruvate;   homofermentation;   homofermentative lactate fermentation;   homofermentative pathway;   homolactate fermentation;   homolactic fermentation
 xref: MetaCyc:ANAEROFRUCAT-PWY


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glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A ISO (MGI:62497|PMID:8224816) MGI PMID:8224816 MGI:62497 NCBI chrNW_004955414:33,087,745...33,100,846 JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chrNW_004955449:3,093,603...3,182,513
Ensembl chrNW_004955449:3,093,603...3,186,737
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase ISO (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chrNW_004955422:18,799,372...18,812,458
Ensembl chrNW_004955422:18,799,372...18,812,711
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    metabolic process 7608
      NAD metabolic process 19
        glucose catabolic process to lactate via pyruvate 5
          negative regulation of glucose catabolic process to lactate via pyruvate 3
          positive regulation of glucose catabolic process to lactate via pyruvate 1
          regulation of glucose catabolic process to lactate via pyruvate + 4
Path 2
Term Annotations click to browse term
  biological_process 11892
    cellular process 11098
      cellular metabolic process 7024
        organic acid metabolic process 628
          oxoacid metabolic process 601
            carboxylic acid metabolic process 597
              monocarboxylic acid metabolic process 397
                lactate metabolic process 17
                  glucose catabolic process to lactate 5
                    glucose catabolic process to lactate via pyruvate 5
                      negative regulation of glucose catabolic process to lactate via pyruvate 3
                      positive regulation of glucose catabolic process to lactate via pyruvate 1
                      regulation of glucose catabolic process to lactate via pyruvate + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.