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ONTOLOGY REPORT - ANNOTATIONS


Term:glucose catabolic process to lactate via pyruvate
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Accession:GO:0019661 term browser browse the term
Definition:The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).
Synonyms:exact_synonym: glucose fermentation to lactate via pyruvate;   homofermentation;   homofermentative lactate fermentation;   homofermentative pathway;   homolactate fermentation;   homolactic fermentation
 xref: MetaCyc:ANAEROFRUCAT-PWY


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glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDHA lactate dehydrogenase A ISO (MGI:62497|PMID:8224816) MGI PMID:8224816 MGI:62497 NCBI chr21:40,829,844...40,840,947 JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr36:16,185,011...16,391,080
Ensembl chr36:16,185,649...16,483,016
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase IEA Ensembl GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    metabolic process 10657
      NAD metabolic process 22
        glucose catabolic process to lactate via pyruvate 5
          negative regulation of glucose catabolic process to lactate via pyruvate 3
          positive regulation of glucose catabolic process to lactate via pyruvate 1
          regulation of glucose catabolic process to lactate via pyruvate + 4
Path 2
Term Annotations click to browse term
  biological_process 16190
    cellular process 15467
      cellular metabolic process 9645
        organic acid metabolic process 865
          oxoacid metabolic process 830
            carboxylic acid metabolic process 814
              monocarboxylic acid metabolic process 530
                lactate metabolic process 19
                  glucose catabolic process to lactate 5
                    glucose catabolic process to lactate via pyruvate 5
                      negative regulation of glucose catabolic process to lactate via pyruvate 3
                      positive regulation of glucose catabolic process to lactate via pyruvate 1
                      regulation of glucose catabolic process to lactate via pyruvate + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.