ONTOLOGY REPORT - ANNOTATIONS


Term:ammonia assimilation cycle
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Accession:GO:0019676 term browser browse the term
Definition:The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.
Synonyms:exact_synonym: glutamate metabolic process via glutamine and ammonia;   glutamate metabolism via glutamine and ammonia
 xref: MetaCyc:AMMASSIM-PWY;   MetaCyc:PWY-3282


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ammonia assimilation cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:1624291
RGD:1600115
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:632694
RGD:2301547
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1624291
RGD:1600115

Term paths to the root
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Term Annotations click to browse term
  biological_process 17895
    nitrogen utilization 6
      ammonia assimilation cycle 3
        negative regulation of ammonia assimilation cycle 0
        positive regulation of ammonia assimilation cycle 1
        regulation of ammonia assimilation cycle + 1
Path 2
Term Annotations click to browse term
  biological_process 17895
    cellular process 16036
      cellular metabolic process 9739
        organic acid metabolic process 981
          oxoacid metabolic process 955
            carboxylic acid metabolic process 912
              cellular amino acid metabolic process 277
                alpha-amino acid metabolic process 204
                  glutamine family amino acid metabolic process 74
                    glutamine metabolic process 23
                      ammonia assimilation cycle 3
                        negative regulation of ammonia assimilation cycle 0
                        positive regulation of ammonia assimilation cycle 1
                        regulation of ammonia assimilation cycle + 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.