ONTOLOGY REPORT - ANNOTATIONS


Term:secondary metabolic process
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Accession:GO:0019748 term browser browse the term
Definition:The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
Synonyms:exact_synonym: secondary metabolism;   secondary metabolite metabolic process;   secondary metabolite metabolism
 xref: Wikipedia:Secondary_metabolism


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secondary metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:13792537
aflatoxin B1 metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 JBrowse link 12 17,382,749 17,387,909 RGD:1624291
RGD:1600115
aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:1304380
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:1624291
RGD:1600115
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:12910550
aflatoxin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:632009
benzylpenicillin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:11081014
coumarin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:1303961
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C JBrowse link 9 95,233,957 95,302,822 RGD:2317077
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:2317077
coumarin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:2306676
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 JBrowse link 1 83,711,223 83,725,222 RGD:727640
RGD:13792537
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 JBrowse link 1 83,744,229 83,766,490 RGD:13792537
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 JBrowse link 1 83,653,248 83,662,118 RGD:13792537
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:1624291
daunorubicin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:1600115
RGD:1624291
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:1624291
RGD:1600115
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:1624291
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:1624291
RGD:13792537
G Akr1c14 aldo-keto reductase family 1, member C14 JBrowse link 17 69,806,095 69,827,125 RGD:13792537
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:1624291
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
RGD:13792537
G Akr7a2 aldo-keto reductase family 7, member A2 JBrowse link 5 157,759,448 157,768,473 RGD:1624291
G Cbr4 carbonyl reductase 4 JBrowse link 16 31,944,328 31,972,553 RGD:1624291
RGD:1600115
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase JBrowse link 17 69,468,427 69,497,132 RGD:13792537
doxorubicin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:1600115
RGD:1624291
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:1624291
RGD:1600115
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:1624291
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:1624291
RGD:13792537
G Akr1c14 aldo-keto reductase family 1, member C14 JBrowse link 17 69,806,095 69,827,125 RGD:13792537
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:1624291
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
RGD:13792537
G Akr7a2 aldo-keto reductase family 7, member A2 JBrowse link 5 157,759,448 157,768,473 RGD:1624291
G Cbr4 carbonyl reductase 4 JBrowse link 16 31,944,328 31,972,553 RGD:1624291
RGD:1600115
G RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase JBrowse link 17 69,468,427 69,497,132 RGD:13792537
hydrogen sulfide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbs cystathionine beta synthase JBrowse link 20 10,361,987 10,386,663 RGD:8554341
RGD:13792537
RGD:1624291
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:1624291
RGD:1600115
G Mpst mercaptopyruvate sulfurtransferase JBrowse link 7 119,626,636 119,631,317 RGD:1600115
RGD:1624291
hydrogen sulfide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ethe1 ETHE1, persulfide dioxygenase JBrowse link 1 81,457,008 81,472,061 RGD:1624291
RGD:13792537
G Sqor sulfide quinone oxidoreductase JBrowse link 3 114,894,944 114,939,375 RGD:1624291
insecticide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:2306660
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 JBrowse link 17 1,579,319 1,610,745 RGD:4890969
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4890969
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:4890969
melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:1624291
RGD:1600115
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1600115
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:1624291
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:1624291
RGD:1600115
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 JBrowse link 8 103,503,982 103,554,905 RGD:1624291
RGD:1600115
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:1624291
RGD:13792537
melanin biosynthetic process from tyrosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
melanin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:1624291
RGD:1600115
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
RGD:1600115
negative regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Slc24a5 solute carrier family 24 member 5 JBrowse link 3 117,335,212 117,354,480 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaa1a acetyl-CoA acyltransferase 1A JBrowse link 8 128,027,880 128,036,471 RGD:13792537
G Acaa1b acetyl-Coenzyme A acyltransferase 1B JBrowse link 8 127,836,235 127,845,296 RGD:13792537
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:1303961
phytoalexin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:5128879
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:5128879
positive regulation of hydrogen sulfide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:1624291
RGD:1600115
positive regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1600115
RGD:1624291
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
RGD:1600115
G Gipc1 GIPC PDZ domain containing family, member 1 JBrowse link 19 24,786,604 24,798,231 RGD:1600115
RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:1624291
RGD:1600115
regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc24a5 solute carrier family 24 member 5 JBrowse link 3 117,335,212 117,354,480 RGD:1600115
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:1624291
RGD:1600115
regulation of pentose-phosphate shunt term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 13 111,946,626 111,996,536 RGD:1625062
G Pgam1 phosphoglycerate mutase 1 JBrowse link 1 261,158,204 261,165,814 RGD:1624291
RGD:1600115
G Tigar TP53 induced glycolysis regulatory phosphatase JBrowse link 4 159,635,145 159,654,108 RGD:1624291
siderophore biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdh2 3-hydroxybutyrate dehydrogenase 2 JBrowse link 2 240,461,505 240,482,149 RGD:1624291
RGD:13792537
RGD:1600115
toxin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:1624291
RGD:1600115
toxin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arl1 ADP-ribosylation factor like GTPase 1 JBrowse link 7 29,282,411 29,293,455 RGD:1624291
RGD:1600115
G As3mt arsenite methyltransferase JBrowse link 1 266,482,787 266,514,570 RGD:625365
RGD:1624291
RGD:1600115
G Atn1 atrophin 1 JBrowse link 4 157,267,394 157,281,199 RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:1624291
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:1624291
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:1600115
RGD:1624291
G Fmo1 flavin containing monooxygenase 1 JBrowse link 13 80,712,885 80,745,095 RGD:1624291
RGD:1600115
G Fmo2 flavin containing monooxygenase 2 JBrowse link 13 80,752,526 80,775,264 RGD:1624291
RGD:1600115
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 JBrowse link 11 27,004,335 27,016,690 RGD:1600115
RGD:1624291
G Pam peptidylglycine alpha-amidating monooxygenase JBrowse link 9 111,028,543 111,177,588 RGD:6483565

Term paths to the root
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Term Annotations click to browse term
  biological_process 17895
    metabolic process 10649
      secondary metabolic process 70
        (+)-kotanin metabolic process + 0
        (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process + 0
        N',N'',N'''-triacetylfusarinine C metabolic process + 0
        arugosin metabolic process + 0
        asperthecin metabolic process + 0
        brevianamide F metabolic process + 0
        cordyol C metabolic process + 0
        cspyrone B1 metabolic process + 0
        cyanogenic glycoside metabolic process + 0
        dehydroaustinol metabolic process + 0
        demethylkotanin metabolic process + 0
        diorcinol metabolic process + 0
        emericellamide metabolic process + 0
        emericellin metabolic process + 0
        emodin metabolic process + 0
        endocrocin metabolic process + 0
        ergot alkaloid metabolic process + 0
        fumagillin biosynthetic process + 0
        gerfelin metabolic process + 0
        glycosinolate metabolic process + 0
        helvolic acid metabolic process + 0
        melanin metabolic process + 20
        monodictyphenone metabolic process + 0
        o-orsellinic acid metabolic process + 0
        ocellus pigment metabolic process + 0
        orcinol metabolic process + 0
        orlandin metabolic process + 0
        penicillin metabolic process + 1
        phenylpropanoid metabolic process + 8
        pheromone metabolic process + 0
        phytochelatin metabolic process + 0
        polyketide metabolic process + 10
        regulation of secondary metabolic process + 14
        secondary metabolite biosynthetic process + 24
        secondary metabolite catabolic process + 0
        shamixanthone metabolic process + 0
        siderophore metabolic process + 1
        tensidol A metabolic process + 0
        tensidol B metabolic process + 0
        terrequinone A metabolic process + 0
        toxin metabolic process + 28
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.