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ONTOLOGY REPORT - ANNOTATIONS


Term:quinolinate biosynthetic process
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Accession:GO:0019805 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
Synonyms:exact_synonym: quinolinate anabolism;   quinolinate biosynthesis;   quinolinate formation;   quinolinate synthesis


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quinolinate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IEA
ISO
GO_REF:0000104
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Htt huntingtin ISO MGI:1861934|MGI:1861935 (MGI:3653320|PMID:16697652) RGD PMID:16697652 MGI:3653320 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase ISO (PMID:9291104) RGD PMID:9291104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO
ISS
IEA
(PMID:12140278)
GO_REF:0000024
GO_REF:0000104
RGD
UniProt
PMID:12140278 GO_REF:0000024, GO_REF:0000104 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        organic cyclic compound metabolic process 5921
          pyridine-containing compound metabolic process 34
            quinolinate metabolic process 6
              quinolinate biosynthetic process 5
                negative regulation of quinolinate biosynthetic process 1
                positive regulation of quinolinate biosynthetic process 0
                regulation of quinolinate biosynthetic process + 1
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        organic acid metabolic process 1008
          oxoacid metabolic process 970
            carboxylic acid metabolic process 951
              dicarboxylic acid metabolic process 103
                dicarboxylic acid biosynthetic process 14
                  quinolinate biosynthetic process 5
                    negative regulation of quinolinate biosynthetic process 1
                    positive regulation of quinolinate biosynthetic process 0
                    regulation of quinolinate biosynthetic process + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.