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ONTOLOGY REPORT - ANNOTATIONS


Term:quinolinate biosynthetic process
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Accession:GO:0019805 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
Synonyms:exact_synonym: quinolinate anabolism;   quinolinate biosynthesis;   quinolinate formation;   quinolinate synthesis


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quinolinate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase NAS
IDA
(PMID:12007609), (PMID:7514594)
(PMID:28792876)
UniProtKB PMID:7514594, PMID:12007609, PMID:28792876 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G HTT huntingtin ISO (MGI:MGI:3653320|PMID:16697652) MGI PMID:16697652 MGI:MGI:3653320 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,422...3,243,960
JBrowse link
G KMO kynurenine 3-monooxygenase IEA UniProtKB GO_REF:0000104 NCBI chr 1:241,531,883...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYNU kynureninase IDA (PMID:9291104) UniProtKB PMID:9291104 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase IDA (PMID:12140278) UniProtKB PMID:12140278 NCBI chr 2:134,838,319...134,902,906
Ensembl chr 2:134,838,616...134,902,034
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18651
    metabolic process 12286
      organic substance metabolic process 11722
        organic cyclic compound metabolic process 6467
          pyridine-containing compound metabolic process 46
            quinolinate metabolic process 6
              quinolinate biosynthetic process 5
                negative regulation of quinolinate biosynthetic process 1
                positive regulation of quinolinate biosynthetic process 0
                regulation of quinolinate biosynthetic process + 1
Path 2
Term Annotations click to browse term
  biological_process 18651
    metabolic process 12286
      cellular metabolic process 11268
        organic acid metabolic process 1264
          oxoacid metabolic process 1242
            carboxylic acid metabolic process 1149
              dicarboxylic acid metabolic process 114
                dicarboxylic acid biosynthetic process 15
                  quinolinate biosynthetic process 5
                    negative regulation of quinolinate biosynthetic process 1
                    positive regulation of quinolinate biosynthetic process 0
                    regulation of quinolinate biosynthetic process + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.