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ONTOLOGY REPORT - ANNOTATIONS


Term:L-ascorbic acid biosynthetic process
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Accession:GO:0019853 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
Synonyms:exact_synonym: L-ascorbic acid anabolism;   L-ascorbic acid biosynthesis;   L-ascorbic acid formation;   L-ascorbic acid synthesis;   ascorbate biosynthesis;   ascorbate biosynthetic process;   vitamin C biosynthesis;   vitamin C biosynthetic process
 xref: MetaCyc:PWY-882


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L-ascorbic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:13825440
RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:70644
G Gulo gulonolactone (L-) oxidase JBrowse link 15 42,671,206 42,693,711 RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:1624291
RGD:13792537
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19676
    metabolic process 11952
      small molecule metabolic process 1833
        monosaccharide metabolic process 288
          monosaccharide biosynthetic process 92
            L-ascorbic acid biosynthetic process 4
              L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
              L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
              negative regulation of L-ascorbic acid biosynthetic process 0
              regulation of L-ascorbic acid biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19676
    metabolic process 11952
      cellular metabolic process 10780
        organic acid metabolic process 1067
          oxoacid metabolic process 1040
            carboxylic acid metabolic process 992
              carboxylic acid biosynthetic process 312
                L-ascorbic acid biosynthetic process 4
                  L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose 0
                  L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate 0
                  negative regulation of L-ascorbic acid biosynthetic process 0
                  regulation of L-ascorbic acid biosynthetic process + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.