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ONTOLOGY REPORT - ANNOTATIONS


Term:cGMP-mediated signaling
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Accession:GO:0019934 term browser browse the term
Definition:Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
Synonyms:exact_synonym: cGMP-mediated signalling


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cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adnp activity-dependent neuroprotector homeobox JBrowse link 3 164,937,188 164,964,819 RGD:1358228
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
G Aqp1 aquaporin 1 (Colton blood group) JBrowse link 4 85,551,503 85,563,683 RGD:1600115
RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:4892585
G Guca2b guanylate cyclase activator 2B JBrowse link 5 138,695,591 138,697,641 RGD:731150
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 JBrowse link 2 180,976,939 181,026,001 RGD:1624291
RGD:13792537
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 JBrowse link 15 45,479,662 45,550,285 RGD:13792537
G Gucy2d guanylate cyclase 2D, retinal JBrowse link 10 55,835,695 55,851,235 RGD:1599625
G Gucy2f guanylate cyclase 2F JBrowse link X 113,372,240 113,474,210 RGD:1599625
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:1624291
G Mrvi1 murine retrovirus integration site 1 homolog JBrowse link 1 175,681,960 175,804,737 RGD:1624291
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:625635
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:729410
RGD:13792537
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:13792537
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1601491
G Npr1 natriuretic peptide receptor 1 JBrowse link 2 189,840,403 189,857,032 RGD:729265
RGD:729410
G Npr2 natriuretic peptide receptor 2 JBrowse link 5 59,128,186 59,147,321 RGD:1601491
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1600115
RGD:13792537
RGD:1624291
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:1624291
RGD:13792537
G Pde9a phosphodiesterase 9A JBrowse link 20 10,123,624 10,216,325 RGD:724613
RGD:13792537
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:13792537
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta JBrowse link 12 17,614,536 17,713,567 RGD:13792537
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha JBrowse link 8 117,486,085 117,548,768 RGD:13792537
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 6 51,265,509 51,356,383 RGD:13792537
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:1624291
negative regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtnr1b melatonin receptor 1B JBrowse link 8 14,359,270 14,373,894 RGD:9588673
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:68285
RGD:13792537
G Pde11a phosphodiesterase 11A JBrowse link 3 62,818,502 63,211,843 RGD:633590
RGD:13792537
G Pde11a_v1 phosphodiesterase 11A, variant 1 RGD:633590
G Pde11a_v2 phosphodiesterase 11A, variant 2 RGD:633590
G Pde11a_v3 phosphodiesterase 11A, variant 3 RGD:633590
RGD:13792537
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1624291
RGD:13792537
G Pdzd3 PDZ domain containing 3 JBrowse link 8 48,577,905 48,582,353 RGD:1600115
RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
nitric oxide-cGMP-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 JBrowse link 2 180,976,939 181,026,001 RGD:1600115
G Kcnc2 potassium voltage-gated channel subfamily C member 2 JBrowse link 7 54,978,453 55,159,362 RGD:10047322
positive regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
G Guca1a guanylate cyclase activator 1A JBrowse link 9 15,609,804 15,620,030 RGD:1599357
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:1626242
RGD:1626243
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:1626243
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1580115
G Npr1 natriuretic peptide receptor 1 JBrowse link 2 189,840,403 189,857,032 RGD:1626243
G Npr2 natriuretic peptide receptor 2 JBrowse link 5 59,128,186 59,147,321 RGD:1626243
G Rundc3a RUN domain containing 3A JBrowse link 10 90,342,033 90,351,172 RGD:1299631
RGD:13792537
regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17968
    signaling 7039
      signal transduction 6529
        intracellular signal transduction 2553
          second-messenger-mediated signaling 463
            cyclic-nucleotide-mediated signaling 230
              cGMP-mediated signaling 41
                negative regulation of cGMP-mediated signaling 9
                nitric oxide-cGMP-mediated signaling pathway 2
                positive regulation of cGMP-mediated signaling 9
                regulation of cGMP-mediated signaling + 19
Path 2
Term Annotations click to browse term
  biological_process 17968
    biological regulation 12664
      regulation of biological process 12002
        regulation of cellular process 11339
          signal transduction 6529
            intracellular signal transduction 2553
              second-messenger-mediated signaling 463
                cyclic-nucleotide-mediated signaling 230
                  cGMP-mediated signaling 41
                    negative regulation of cGMP-mediated signaling 9
                    nitric oxide-cGMP-mediated signaling pathway 2
                    positive regulation of cGMP-mediated signaling 9
                    regulation of cGMP-mediated signaling + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.