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ONTOLOGY REPORT - ANNOTATIONS


Term:cyclic-nucleotide-mediated signaling
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Accession:GO:0019935 term browser browse the term
Definition:Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.
Synonyms:exact_synonym: cyclic-nucleotide-mediated signalling


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adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy9 adenylate cyclase 9 JBrowse link 10 11,392,698 11,515,406 RGD:1624291
RGD:1600115
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:13792537
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:13792537
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:13792537
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
RGD:13792537
G Adra2b adrenoceptor alpha 2B JBrowse link 3 119,805,941 119,809,987 RGD:13792537
G Adra2c adrenoceptor alpha 2C JBrowse link 14 80,730,307 80,732,010 RGD:13792537
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:1600115
RGD:13792537
RGD:1624291
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:13792537
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:13792537
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:13792537
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:13792537
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:13792537
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1624291
RGD:1600115
G Gpr101 G protein-coupled receptor 101 JBrowse link X 140,296,220 140,303,743 RGD:13792537
G LOC500460 similar to olfactory receptor Olr841 JBrowse link 5 64,614,755 64,615,714 RGD:13792537
G Olr1257 olfactory receptor 1257 JBrowse link 8 42,429,993 42,430,928 RGD:13792537
G Olr1320 olfactory receptor 1320 JBrowse link 8 43,628,182 43,629,120 RGD:13792537
G Olr533 olfactory receptor 533 JBrowse link 3 74,574,075 74,575,010 RGD:13792537
G Olr841 olfactory receptor 841 JBrowse link 5 64,621,407 64,622,359 RGD:13792537
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1600115
RGD:1624291
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:6906968
RGD:13792537
adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:1624291
RGD:1600115
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
RGD:1600115
adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:7327160
adenylate cyclase-activating dopamine receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:1624291
RGD:1600115
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:1581394
RGD:1624291
RGD:8553617
RGD:1600115
RGD:8554146
RGD:7248551
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:1624291
RGD:1600115
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:1581394
RGD:1624291
RGD:1600115
RGD:1600979
G Gnal G protein subunit alpha L JBrowse link 18 62,805,406 62,946,133 RGD:1624291
RGD:13792537
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8553387
RGD:13792537
RGD:1624291
G Oprd1 opioid receptor, delta 1 JBrowse link 5 150,288,126 150,323,063 RGD:1624291
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
RGD:1600115
G Ptger1 prostaglandin E receptor 1 JBrowse link 19 24,799,422 24,803,373 RGD:1600115
RGD:1624291
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1624291
RGD:1600115
adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:1624291
RGD:1600115
G Adcy1 adenylate cyclase 1 JBrowse link 14 87,311,970 87,429,880 RGD:13792537
G Adcy2 adenylate cyclase 2 JBrowse link 1 37,043,071 37,698,390 RGD:10400854
RGD:13792537
G Adcy3 adenylate cyclase 3 JBrowse link 6 28,570,941 28,648,848 RGD:1600115
RGD:13792537
RGD:1624291
G Adcy4 adenylate cyclase 4 JBrowse link 15 34,453,917 34,469,779 RGD:13792537
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:1624291
RGD:13792537
RGD:1600115
RGD:2316039
G Adcy6 adenylate cyclase 6 JBrowse link 7 140,270,678 140,291,722 RGD:1600115
RGD:13792537
RGD:1624291
G Adcy7 adenylate cyclase 7 JBrowse link 19 19,702,307 19,762,973 RGD:2316039
RGD:13792537
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:8553299
RGD:13792537
G Adcy9 adenylate cyclase 9 JBrowse link 10 11,392,698 11,515,406 RGD:1624291
RGD:13792537
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:1624291
RGD:13792537
RGD:2325271
RGD:8554017
G Adgrb1 adhesion G protein-coupled receptor B1 JBrowse link 7 115,766,484 115,828,514 RGD:13792537
G Adgrb2 adhesion G protein-coupled receptor B2 JBrowse link 5 148,168,530 148,231,587 RGD:13792537
G Adgrb3 adhesion G protein-coupled receptor B3 JBrowse link 9 31,280,623 32,022,535 RGD:13792537
G Adgrd1 adhesion G protein-coupled receptor D1 JBrowse link 12 31,134,806 31,249,594 RGD:1624291
RGD:13792537
G Adgre1 adhesion G protein-coupled receptor E1 JBrowse link 9 9,431,888 9,585,883 RGD:13792537
G Adgre4 adhesion G protein-coupled receptor E4 JBrowse link 9 8,056,034 8,200,262 RGD:13792537
G Adgre5 adhesion G protein-coupled receptor E5 JBrowse link 19 24,854,981 24,875,712 RGD:13792537
G Adgrf1 adhesion G protein-coupled receptor F1 JBrowse link 9 20,343,730 20,378,686 RGD:1624291
G Adgrg1 adhesion G protein-coupled receptor G1 JBrowse link 19 10,423,534 10,460,674 RGD:13792537
G Adgrg2 adhesion G protein-coupled receptor G2 JBrowse link X 36,930,186 37,054,968 RGD:13792537
G Adgrg3 adhesion G protein-coupled receptor G3 JBrowse link 19 10,392,001 10,422,606 RGD:13792537
G Adgrg4 adhesion G protein-coupled receptor G4 JBrowse link X 159,286,775 159,437,536 RGD:13792537
G Adgrg5 adhesion G protein-coupled receptor G5 JBrowse link 19 10,495,517 10,514,701 RGD:13792537
G Adgrg6 adhesion G protein-coupled receptor G6 JBrowse link 1 8,593,342 8,751,540 RGD:1624291
RGD:13792537
G Adgrg7 adhesion G protein-coupled receptor G7 JBrowse link 11 46,103,173 46,172,303 RGD:13792537
G Adgrl1 adhesion G protein-coupled receptor L1 JBrowse link 19 25,029,037 25,069,146 RGD:13792537
G Adgrl2 adhesion G protein-coupled receptor L2 JBrowse link 2 258,792,838 258,997,145 RGD:13792537
G Adgrl3 adhesion G protein-coupled receptor L3 JBrowse link 14 28,362,176 29,226,085 RGD:13792537
G Adgrl4 adhesion G protein-coupled receptor L4 JBrowse link 2 256,609,787 256,724,642 RGD:13792537
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1600115
RGD:1624291
G Adm2 adrenomedullin 2 JBrowse link 7 130,296,895 130,298,641 RGD:1304019
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625630
RGD:1624291
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1600115
RGD:1624291
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:1624291
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:2301952
RGD:1624291
RGD:1600115
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:632162
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
RGD:13792537
G Calcb calcitonin-related polypeptide, beta JBrowse link 1 184,271,116 184,276,480 RGD:13792537
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:1624291
RGD:1600115
G Calcrl calcitonin receptor like receptor JBrowse link 3 71,747,938 71,845,487 RGD:1624291
RGD:1600115
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:1626241
RGD:1600115
RGD:1624291
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:1600115
RGD:1624291
G Cxcl11 C-X-C motif chemokine ligand 11 JBrowse link 14 17,195,395 17,198,170 RGD:1600115
RGD:1624291
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:1600115
RGD:1624291
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:1624291
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:1624291
G Drd5 dopamine receptor D5 JBrowse link 14 77,220,579 77,222,006 RGD:1624291
RGD:728422
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:625417
RGD:13792537
RGD:1601258
G Galr1 galanin receptor 1 JBrowse link 18 79,243,009 79,258,570 RGD:1625746
G Galr2 galanin receptor 2 JBrowse link 10 105,156,793 105,159,221 RGD:1625746
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1600115
RGD:1624291
G Gcgr glucagon receptor JBrowse link 10 109,707,863 109,716,253 RGD:728550
RGD:1624291
RGD:1625209
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:628502
RGD:13792537
RGD:1624291
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624291
RGD:1600115
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:1598447
RGD:1600115
RGD:1624291
G Gna13 G protein subunit alpha 13 JBrowse link 10 97,647,196 97,680,030 RGD:1624291
RGD:13792537
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13507308
G Gnal G protein subunit alpha L JBrowse link 18 62,805,406 62,946,133 RGD:1624291
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1624291
RGD:13792537
RGD:1600115
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1601381
RGD:1624291
RGD:5509804
RGD:2315004
RGD:2313211
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1600115
RGD:1624291
G Gpha2 glycoprotein hormone subunit alpha 2 JBrowse link 1 221,594,110 221,597,297 RGD:1600115
RGD:1624291
G Gphb5 glycoprotein hormone subunit beta 5 JBrowse link 6 98,380,500 98,383,049 RGD:1600115
RGD:1624291
G Gpr161 G protein-coupled receptor 161 JBrowse link 13 83,530,389 83,576,117 RGD:1624291
RGD:1600115
G Gpr26 G protein-coupled receptor 26 JBrowse link 1 203,971,152 203,988,709 RGD:1624291
RGD:13792537
RGD:1600115
G Gpr3 G protein-coupled receptor 3 JBrowse link 5 151,394,118 151,397,634 RGD:1624291
G Gpr65 G-protein coupled receptor 65 JBrowse link 6 122,248,528 122,256,115 RGD:1624291
RGD:1600115
G Htr4 5-hydroxytryptamine receptor 4 JBrowse link 18 57,637,013 57,820,317 RGD:729350
G Iapp islet amyloid polypeptide JBrowse link 4 176,509,863 176,517,903 RGD:12907560
RGD:1624291
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 JBrowse link 7 58,447,097 58,587,787 RGD:13792537
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:1600115
RGD:13792537
RGD:1624291
G LOC103692150 thyrotropin receptor pseudogene JBrowse link 4 93,447,412 93,448,194 RGD:1624291
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:1624291
G Mc2r melanocortin 2 receptor JBrowse link 18 64,166,959 64,178,729 RGD:1624291
RGD:1600115
G Mc3r melanocortin 3 receptor JBrowse link 3 170,252,901 170,253,998 RGD:1624291
RGD:1600115
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:1624291
RGD:1600115
G Mc5r melanocortin 5 receptor JBrowse link 18 64,113,659 64,118,700 RGD:1624291
RGD:1600115
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 JBrowse link 10 81,648,216 81,653,717 RGD:2299078
G Pf4 platelet factor 4 JBrowse link 14 18,848,549 18,849,258 RGD:1600115
RGD:1624291
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:13792537
G Ptgdrl prostaglandin D2 receptor-like JBrowse link 15 18,089,077 18,095,979 RGD:13792537
G Ptger1 prostaglandin E receptor 1 JBrowse link 19 24,799,422 24,803,373 RGD:13792537
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:1624291
RGD:13792537
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:13792537
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:13792537
G Ptgfr prostaglandin F receptor JBrowse link 2 257,005,813 257,039,036 RGD:13792537
G Ptgir prostaglandin I2 receptor JBrowse link 1 78,833,449 78,835,832 RGD:1624291
RGD:13792537
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:1601517
RGD:1624291
RGD:12793028
G Pth1r parathyroid hormone 1 receptor JBrowse link 8 118,984,531 119,012,803 RGD:1624291
RGD:8553376
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:729903
RGD:13792537
RGD:1624291
G Ramp1 receptor activity modifying protein 1 JBrowse link 9 98,313,632 98,364,206 RGD:1600115
RGD:1624291
G Ramp2 receptor activity modifying protein 2 JBrowse link 10 89,166,170 89,168,962 RGD:1600115
RGD:1624291
G Ramp3 receptor activity modifying protein 3 JBrowse link 14 86,922,223 86,939,722 RGD:1600115
RGD:1624291
G Rit2 Ras-like without CAAX 2 JBrowse link 18 23,700,012 24,057,917 RGD:2325271
G Rxfp1 relaxin family peptide receptor 1 JBrowse link 2 178,402,411 178,520,213 RGD:1304481
RGD:13792537
G Rxfp2 relaxin family peptide receptor 2 JBrowse link 12 6,016,884 6,078,411 RGD:1624291
RGD:13792537
G S1pr4 sphingosine-1-phosphate receptor 4 JBrowse link 7 11,077,411 11,079,687 RGD:1624291
RGD:1600115
G Tbxa2r thromboxane A2 receptor JBrowse link 7 11,253,153 11,259,233 RGD:13792537
G Tshr thyroid stimulating hormone receptor JBrowse link 6 115,170,290 115,306,871 RGD:1600115
RGD:13792537
RGD:1624291
G Ucn2 urocortin 2 JBrowse link 8 117,727,216 117,728,765 RGD:1600115
RGD:13792537
RGD:1624291
G Ucn3 urocortin 3 JBrowse link 17 69,959,879 69,966,532 RGD:1624291
RGD:13792537
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:1624291
RGD:13792537
RGD:1600115
RGD:8554017
adenylate cyclase-activating serotonin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:625369
cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy2 adenylate cyclase 2 JBrowse link 1 37,043,071 37,698,390 RGD:10400854
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:69741
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:8554519
RGD:1624291
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:631732
G Adgrg6 adhesion G protein-coupled receptor G6 JBrowse link 1 8,593,342 8,751,540 RGD:1624291
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:628358
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Crem cAMP responsive element modulator JBrowse link 17 57,021,704 57,090,888 RGD:1298796
G Defb1 defensin beta 1 JBrowse link 16 75,294,385 75,309,127 RGD:1624291
RGD:1600115
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
RGD:1600115
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 JBrowse link 20 31,055,292 31,072,469 RGD:1624291
RGD:1600115
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:8554330
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:1624291
RGD:1600115
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link 4 157,676,336 157,680,322 RGD:13792662
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624951
RGD:1624291
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:1598448
RGD:1624291
G Htr5a 5-hydroxytryptamine receptor 5A JBrowse link 4 199,916 209,599 RGD:1624291
RGD:1600115
G Ksr1 kinase suppressor of ras 1 JBrowse link 10 66,323,704 66,342,469 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:625547
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 JBrowse link 2 46,372,488 46,476,162 RGD:1624291
RGD:1600115
G Pclo piccolo (presynaptic cytomatrix protein) JBrowse link 4 16,454,904 17,058,921 RGD:1624291
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1600115
RGD:13792537
RGD:1624291
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:1624291
RGD:13792537
G Pde7a phosphodiesterase 7A JBrowse link 2 104,042,124 104,134,101 RGD:731232
G Pde7b phosphodiesterase 7B JBrowse link 1 15,889,845 16,203,909 RGD:625534
G Pde7b_v3 phosphodiesterase 7B, variant 3 RGD:625534
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:1600115
RGD:1624291
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
RGD:1600115
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:8553866
RGD:1624291
cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adnp activity-dependent neuroprotector homeobox JBrowse link 3 164,937,188 164,964,819 RGD:1358228
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
G Aqp1 aquaporin 1 (Colton blood group) JBrowse link 4 85,551,503 85,563,683 RGD:1600115
RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:4892585
G Guca2b guanylate cyclase activator 2B JBrowse link 5 138,695,591 138,697,641 RGD:731150
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 JBrowse link 2 180,976,939 181,026,001 RGD:1624291
RGD:13792537
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 JBrowse link 15 45,479,662 45,550,285 RGD:13792537
G Gucy2d guanylate cyclase 2D, retinal JBrowse link 10 55,835,695 55,851,235 RGD:1599625
G Gucy2f guanylate cyclase 2F JBrowse link X 113,372,240 113,474,210 RGD:1599625
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:1624291
G Mrvi1 murine retrovirus integration site 1 homolog JBrowse link 1 175,681,960 175,804,737 RGD:1624291
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:625635
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:729410
RGD:13792537
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:13792537
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1601491
G Npr1 natriuretic peptide receptor 1 JBrowse link 2 189,840,403 189,857,032 RGD:729265
RGD:729410
G Npr2 natriuretic peptide receptor 2 JBrowse link 5 59,128,186 59,147,321 RGD:1601491
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1600115
RGD:13792537
RGD:1624291
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:1624291
RGD:13792537
G Pde9a phosphodiesterase 9A JBrowse link 20 10,123,624 10,216,325 RGD:724613
RGD:13792537
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:13792537
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta JBrowse link 12 17,614,536 17,713,567 RGD:13792537
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha JBrowse link 8 117,486,085 117,548,768 RGD:13792537
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 6 51,265,509 51,356,383 RGD:13792537
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:1624291
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrdc3 arrestin domain containing 3 JBrowse link 2 8,732,907 8,745,445 RGD:1624291
RGD:1600115
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1600115
RGD:1624291
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13508593
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:1624291
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplp1 amyloid beta precursor like protein 1 JBrowse link 1 88,897,525 88,908,750 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13792694
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:13792694
G Mrap melanocortin 2 receptor accessory protein JBrowse link 11 30,904,733 30,915,225 RGD:1624291
G Mrap2 melanocortin 2 receptor accessory protein 2 JBrowse link 8 94,801,336 94,858,192 RGD:1624291
RGD:1600115
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835006
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:9835006
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:9850263
G Sstr4 somatostatin receptor 4 JBrowse link 3 142,739,781 142,741,644 RGD:2325010
negative regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplnr apelin receptor JBrowse link 3 72,540,538 72,544,183 RGD:12907555
RGD:13792537
RGD:1600115
RGD:1624291
G Cdc34 cell division cycle 34 JBrowse link 7 12,899,957 12,905,339 RGD:1624291
RGD:1600115
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:1624291
G Crtc3 CREB regulated transcription coactivator 3 JBrowse link 1 142,398,248 142,500,562 RGD:1624291
RGD:1600115
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:727395
G Mgrn1 mahogunin ring finger 1 JBrowse link 10 10,832,573 10,881,999 RGD:1600115
RGD:13792537
RGD:1624291
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:633494
G Nucb2 nucleobindin 2 JBrowse link 1 185,106,773 185,143,278 RGD:9831186
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835005
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
RGD:1600115
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:68285
G Pde11a phosphodiesterase 11A JBrowse link 3 62,818,502 63,211,843 RGD:633590
RGD:13792537
G Pde11a_v1 phosphodiesterase 11A, variant 1 RGD:633590
G Pde11a_v2 phosphodiesterase 11A, variant 2 RGD:633590
G Pde11a_v3 phosphodiesterase 11A, variant 3 RGD:633590
RGD:13792537
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:625635
RGD:13792537
RGD:1624291
RGD:1600115
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:2312525
RGD:13792537
RGD:1624291
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:2312525
RGD:13792537
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1600115
RGD:13792537
RGD:1624291
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:1624291
RGD:1600115
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
negative regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtnr1b melatonin receptor 1B JBrowse link 8 14,359,270 14,373,894 RGD:9588673
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:68285
RGD:13792537
G Pde11a phosphodiesterase 11A JBrowse link 3 62,818,502 63,211,843 RGD:633590
RGD:13792537
G Pde11a_v1 phosphodiesterase 11A, variant 1 RGD:633590
G Pde11a_v2 phosphodiesterase 11A, variant 2 RGD:633590
G Pde11a_v3 phosphodiesterase 11A, variant 3 RGD:633590
RGD:13792537
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1624291
RGD:13792537
G Pdzd3 PDZ domain containing 3 JBrowse link 8 48,577,905 48,582,353 RGD:1600115
RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
RGD:1600115
nitric oxide-cGMP-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 JBrowse link 2 180,976,939 181,026,001 RGD:1600115
G Kcnc2 potassium voltage-gated channel subfamily C member 2 JBrowse link 7 54,978,453 55,159,362 RGD:10047322
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1600115
RGD:1624291
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129138
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1600115
RGD:1624291
G Mrap melanocortin 2 receptor accessory protein JBrowse link 11 30,904,733 30,915,225 RGD:1624291
G Mrap2 melanocortin 2 receptor accessory protein 2 JBrowse link 8 94,801,336 94,858,192 RGD:1624291
RGD:1600115
positive regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325275
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:2315974
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:2316150
RGD:631750
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
RGD:13792537
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:6906968
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:70047
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:5491010
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5131269
RGD:1624291
RGD:5491010
RGD:5491003
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:7243859
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:1624957
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:2312537
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:2312607
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1624291
RGD:1600115
G Gpr3 G protein-coupled receptor 3 JBrowse link 5 151,394,118 151,397,634 RGD:632931
G Gpr61 G protein-coupled receptor 61 JBrowse link 2 210,937,289 210,943,727 RGD:1600115
RGD:1624291
G Gpr62 G protein-coupled receptor 62 JBrowse link 8 115,165,655 115,170,396 RGD:1600115
RGD:1624291
G Insl3 insulin-like 3 JBrowse link 16 20,120,753 20,122,702 RGD:633070
G Olr59 olfactory receptor 59 JBrowse link 1 167,906,030 167,940,688 RGD:1600115
RGD:1624291
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2302817
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10003101
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10003101
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1600115
RGD:1624291
G Rxfp2 relaxin family peptide receptor 2 JBrowse link 12 6,016,884 6,078,411 RGD:1600172
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:9590237
G Sctr secretin receptor JBrowse link 13 36,039,241 36,090,515 RGD:9590237
RGD:1624291
G Taar1 trace-amine-associated receptor 1 JBrowse link 1 22,595,477 22,596,475 RGD:11531774
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:70047
positive regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
RGD:13792537
G Guca1a guanylate cyclase activator 1A JBrowse link 9 15,609,804 15,620,030 RGD:1599357
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:1626242
RGD:1626243
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:1626243
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1580115
G Npr1 natriuretic peptide receptor 1 JBrowse link 2 189,840,403 189,857,032 RGD:1626243
G Npr2 natriuretic peptide receptor 2 JBrowse link 5 59,128,186 59,147,321 RGD:1626243
G Rundc3a RUN domain containing 3A JBrowse link 10 90,342,033 90,351,172 RGD:1299631
RGD:13792537
regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai1 G protein subunit alpha i1 JBrowse link 4 13,405,136 13,486,866 RGD:10449520
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:1624291
G Pde4a phosphodiesterase 4A JBrowse link 8 22,189,533 22,234,036 RGD:1624291
RGD:1600115
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:2312596
G Pex5l peroxisomal biogenesis factor 5-like JBrowse link 2 119,330,330 119,405,809 RGD:8553454
G Rasd2 RASD family, member 2 JBrowse link 19 14,653,198 14,663,914 RGD:1304287
G Tcp11 t-complex 11 JBrowse link 20 7,645,619 7,657,222 RGD:1624291
RGD:1600115
regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        intracellular signal transduction 2565
          second-messenger-mediated signaling 465
            cyclic-nucleotide-mediated signaling 228
              cAMP-mediated signaling + 196
              cGMP-mediated signaling + 41
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of cellular process 11458
          signal transduction 6597
            intracellular signal transduction 2565
              second-messenger-mediated signaling 465
                cyclic-nucleotide-mediated signaling 228
                  cAMP-mediated signaling + 196
                  cGMP-mediated signaling + 41
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.