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ONTOLOGY REPORT - ANNOTATIONS


Term:chemokine binding
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Accession:GO:0019956 term browser browse the term
Definition:Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


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chemokine binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr2 atypical chemokine receptor 2 JBrowse link 8 130,526,521 130,543,566 RGD:13792537
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:13792537
G Ackr4 atypical chemokine receptor 4 JBrowse link 8 112,643,838 112,651,668 RGD:13792537
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:13792537
G Ccr10 C-C motif chemokine receptor 10 JBrowse link 10 89,086,556 89,088,993 RGD:13792537
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 JBrowse link 8 133,127,220 133,128,290 RGD:13792537
G Ccr2 C-C motif chemokine receptor 2 RGD:13792537
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:13792537
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:13792537
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:13792537
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:13792537
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:13792537
G Ccr8 C-C motif chemokine receptor 8 JBrowse link 8 128,779,552 128,782,531 RGD:13792537
G Ccr9 C-C motif chemokine receptor 9 JBrowse link 8 132,827,325 132,842,130 RGD:13792537
G Ccrl2 C-C motif chemokine receptor like 2 JBrowse link 8 119,324,298 119,326,954 RGD:13792537
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:13792537
G Cxcr1 C-X-C motif chemokine receptor 1 JBrowse link 9 81,466,430 81,469,299 RGD:13792537
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:13792537
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:1624291
RGD:13792537
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:13792537
G Cxcr5 C-X-C motif chemokine receptor 5 JBrowse link 8 48,835,688 48,852,032 RGD:13792537
G Cxcr6 C-X-C motif chemokine receptor 6 JBrowse link 8 132,869,712 132,870,766 RGD:13792537
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1624291
G Plp2 proteolipid protein 2 JBrowse link X 15,679,254 15,682,653 RGD:1624291
G Xcr1 X-C motif chemokine receptor 1 JBrowse link 8 132,911,474 132,919,110 RGD:13792537
C-C chemokine binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr1 atypical chemokine receptor 1 JBrowse link 13 91,827,310 91,828,875 RGD:1624291
G Ackr2 atypical chemokine receptor 2 JBrowse link 8 130,526,521 130,543,566 RGD:1624291
RGD:13792537
RGD:1600115
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:13792537
G Ackr4 atypical chemokine receptor 4 JBrowse link 8 112,643,838 112,651,668 RGD:13792537
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:5688180
RGD:13792537
RGD:1624291
G Ccr10 C-C motif chemokine receptor 10 JBrowse link 10 89,086,556 89,088,993 RGD:13792537
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 JBrowse link 8 133,127,220 133,128,290 RGD:13792537
G Ccr2 C-C motif chemokine receptor 2 RGD:13792537
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:1600115
RGD:13792537
RGD:1624291
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:13792537
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:1624291
RGD:13792537
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:1624291
RGD:13792537
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:13792537
G Ccr8 C-C motif chemokine receptor 8 JBrowse link 8 128,779,552 128,782,531 RGD:13792537
G Ccr9 C-C motif chemokine receptor 9 JBrowse link 8 132,827,325 132,842,130 RGD:13792537
G Ccrl2 C-C motif chemokine receptor like 2 JBrowse link 8 119,324,298 119,326,954 RGD:13792537
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:13792537
G Cxcr1 C-X-C motif chemokine receptor 1 JBrowse link 9 81,466,430 81,469,299 RGD:13792537
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:13792537
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:13792537
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:1624291
RGD:13792537
G Cxcr5 C-X-C motif chemokine receptor 5 JBrowse link 8 48,835,688 48,852,032 RGD:13792537
G Cxcr6 C-X-C motif chemokine receptor 6 JBrowse link 8 132,869,712 132,870,766 RGD:13792537
G Xcr1 X-C motif chemokine receptor 1 JBrowse link 8 132,911,474 132,919,110 RGD:13792537
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
C-X-C chemokine binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:1624291
RGD:1600115
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:1624291
RGD:1600115
G Cxcr6 C-X-C motif chemokine receptor 6 JBrowse link 8 132,869,712 132,870,766 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
C-X3-C chemokine binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1624291
RGD:1600115
G Itga4 integrin subunit alpha 4 JBrowse link 3 66,178,745 66,265,547 RGD:1624291
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:1624291
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1600115
RGD:13792537
RGD:1624291
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:1624291
chemokine (C-C motif) ligand 12 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
chemokine (C-C motif) ligand 19 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:1624291
RGD:13792537
chemokine (C-C motif) ligand 2 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
chemokine (C-C motif) ligand 21 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:1624291
RGD:13792537
chemokine (C-C motif) ligand 5 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:1624291
RGD:13792537
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 JBrowse link 8 133,127,220 133,128,290 RGD:13792537
G Ccr2 C-C motif chemokine receptor 2 RGD:13792537
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:1600115
RGD:13792537
RGD:1624291
chemokine (C-C motif) ligand 7 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:1624291
RGD:13792537
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 JBrowse link 8 133,127,220 133,128,290 RGD:13792537
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
interleukin-8 binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:1624291
G Cxcr1 C-X-C motif chemokine receptor 1 JBrowse link 9 81,466,430 81,469,299 RGD:1624291
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:1600115
RGD:1624291

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  molecular_function 19528
    binding 15911
      protein binding 12626
        cytokine binding 142
          chemokine binding 34
            C-C chemokine binding + 25
            C-X-C chemokine binding + 7
            C-X3-C chemokine binding 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.