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ONTOLOGY REPORT - ANNOTATIONS


Term:roof plate formation
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Accession:GO:0021509 term browser browse the term
Definition:The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.


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roof plate formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdf7 growth differentiation factor 7 ISO MGI:2386906 (MGI:1353705|PMID:10693795) RGD PMID:10693795 MGI:1353705 NCBI chr 6:33,496,596...33,507,626
Ensembl chr 6:33,503,217...33,507,542
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  biological_process 20020
    developmental process 6826
      anatomical structure formation involved in morphogenesis 1214
        roof plate formation 1
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  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          tube development 1210
            tube morphogenesis 934
              epithelial tube morphogenesis 399
                epithelial tube formation 167
                  embryonic epithelial tube formation 156
                    neural tube formation 134
                      roof plate formation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.