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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord dorsal/ventral patterning
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Accession:GO:0021513 term browser browse the term
Definition:The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms:exact_synonym: spinal cord dorsoventral patterning


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spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FUZ fuzzy planar cell polarity protein ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chr19:46,819,833...46,826,235
Ensembl chr19:55,736,325...55,742,589
JBrowse link
G GLI2 GLI family zinc finger 2 ISO (MGI:3612806|PMID:16364285)
(MGI:2154468|PMID:11748151)
(MGI:3051712|PMID:15215207)
MGI PMID:11748151, PMID:15215207, PMID:16364285 MGI:2154468, MGI:3051712, MGI:3612806 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G GLI3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207)
(MGI:3612806|PMID:16364285)
MGI PMID:15215207, PMID:16364285 MGI:3051712, MGI:3612806 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865
JBrowse link
G IFT88 intraflagellar transport 88 ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chr13:1,893,102...2,017,771
Ensembl chr13:20,206,471...20,331,204
JBrowse link
G INTU inturned planar cell polarity protein ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chr 4:119,793,245...119,890,949
Ensembl chr 4:131,109,733...131,186,590
JBrowse link
G RAB23 RAB23, member RAS oncogene family ISO (MGI:3612806|PMID:16364285)
(MGI:3577662|PMID:15755804), (MGI:3612806|PMID:16364285)
(MGI:2679893|PMID:14603322)
MGI PMID:14603322, PMID:15755804, PMID:16364285 MGI:2679893, MGI:3577662, MGI:3612806 NCBI chr 6:56,744,948...56,780,187
Ensembl chr 6:58,375,559...58,411,107
JBrowse link
G SHH sonic hedgehog signaling molecule ISO PMID:9230312
(MGI:2154468|PMID:11748151)
MGI PMID:9230312, PMID:11748151 MGI:2154468, RGD:8553789 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:3616741|PMID:16459298) MGI PMID:16459298 MGI:3616741 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472
JBrowse link
BMP signaling pathway involved in spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRD chordin ISO (PMID:11472837) BHF-UCL PMID:11472837 NCBI chr 3:181,417,140...181,460,236
Ensembl chr 3:189,898,856...189,908,573
JBrowse link
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100990238 intraflagellar transport protein 122 homolog ISO (MGI:4888042|PMID:21209331) BHF-UCL PMID:21209331 MGI:4888042 NCBI chr 3:126,498,018...126,578,211
Ensembl chr 3:133,851,433...133,930,117
JBrowse link
G RFX4 regulatory factor X4 ISO (MGI:5430880|PMID:19887680) MGI PMID:19887680 MGI:5430880 NCBI chr12:104,152,816...104,330,383
Ensembl chr12:107,550,254...107,724,623
JBrowse link
G TULP3 TUB like protein 3 ISO (MGI:3841503|PMID:19286674) MGI PMID:19286674 MGI:3841503 NCBI chr12:3,012,890...3,061,831
Ensembl chr12:2,944,769...2,993,278
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G GLI3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G GLI3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472
JBrowse link
smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMO smoothened, frizzled class receptor ISO (MGI:4888042|PMID:21209331)
(MGI:3841503|PMID:19286674)
CACAO
MGI
PMID:19286674, PMID:21209331 MGI:3841503, MGI:4888042 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048
JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 ISO (MGI:3587461|PMID:16020526) UniProt PMID:16020526 MGI:3587461 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999
JBrowse link
G DLL4 delta like canonical Notch ligand 4 ISO (PMID:17728344) UniProtKB PMID:17728344 NCBI chr15:19,871,584...19,881,817
Ensembl chr15:38,121,574...38,129,471
JBrowse link
G FOXN4 forkhead box N4 ISO (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) UniProt PMID:16020526, PMID:17728344 MGI:3587461, MGI:3765356 NCBI chr12:106,855,308...106,886,508
Ensembl chr12:110,251,449...110,280,025
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-2 NK2 homeobox 2 ISO (MGI:1334824|PMID:10217145) MGI PMID:10217145 MGI:1334824 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBX1 developing brain homeobox 1 ISO (MGI:2136554|PMID:11239429) MGI PMID:11239429 MGI:2136554 NCBI chr11:20,180,704...20,185,164
Ensembl chr11:20,092,540...20,097,727
JBrowse link
G DMRT3 doublesex and mab-3 related transcription factor 3 ISO (MGI:5435948|PMID:22932389) MGI PMID:22932389 MGI:5435948 NCBI chr 9:786,402...801,114 JBrowse link
G LHX3 LIM homeobox 3 ISO (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366
JBrowse link
G SHH sonic hedgehog signaling molecule ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651
JBrowse link
G SOX1 SRY-box transcription factor 1 ISO (MGI:4834949|PMID:20844123) MGI PMID:20844123 MGI:4834949 NCBI chr13:93,023,958...93,269,467 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    multicellular organismal process 6470
      pattern specification process 452
        regionalization 364
          spinal cord patterning 23
            spinal cord dorsal/ventral patterning 21
              BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
              retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
              smoothened signaling pathway involved in ventral spinal cord patterning + 7
              ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 12566
    developmental process 5839
      anatomical structure development 5452
        multicellular organism development 4984
          system development 4688
            nervous system development 2406
              central nervous system development 1164
                spinal cord development 135
                  spinal cord patterning 23
                    spinal cord dorsal/ventral patterning 21
                      BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
                      negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
                      retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
                      smoothened signaling pathway involved in ventral spinal cord patterning + 7
                      ventral spinal cord interneuron fate commitment + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.