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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord dorsal/ventral patterning
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Accession:GO:0021513 term browser browse the term
Definition:The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms:exact_synonym: spinal cord dorsoventral patterning


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spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chrNW_004955559:1,112,670...1,117,620
Ensembl chrNW_004955559:1,112,855...1,117,413
JBrowse link
G Gli2 GLI family zinc finger 2 ISO (MGI:3612806|PMID:16364285)
(MGI:3051712|PMID:15215207)
(MGI:2154468|PMID:11748151)
MGI PMID:11748151, PMID:15215207, PMID:16364285 MGI:2154468, MGI:3051712, MGI:3612806 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499
JBrowse link
G Gli3 GLI family zinc finger 3 ISO (MGI:3612806|PMID:16364285)
(MGI:3051712|PMID:15215207)
MGI PMID:15215207, PMID:16364285 MGI:3051712, MGI:3612806 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918
JBrowse link
G Ift88 intraflagellar transport 88 ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chrNW_004955497:1,338,959...1,454,788
Ensembl chrNW_004955497:1,338,904...1,455,122
JBrowse link
G Intu inturned planar cell polarity protein ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chrNW_004955428:13,670,756...13,743,030
Ensembl chrNW_004955428:13,668,774...13,743,090
JBrowse link
G Rab23 RAB23, member RAS oncogene family ISO (MGI:3612806|PMID:16364285)
(MGI:2679893|PMID:14603322)
(MGI:3577662|PMID:15755804), (MGI:3612806|PMID:16364285)
MGI PMID:14603322, PMID:15755804, PMID:16364285 MGI:2679893, MGI:3577662, MGI:3612806 NCBI chrNW_004955502:2,947,170...2,980,634
Ensembl chrNW_004955502:2,950,562...2,980,634
JBrowse link
G Shh sonic hedgehog signaling molecule ISO PMID:9230312
(MGI:2154468|PMID:11748151)
MGI PMID:9230312, PMID:11748151 MGI:2154468, RGD:8553789 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:3616741|PMID:16459298) MGI PMID:16459298 MGI:3616741 NCBI chrNW_004955485:7,805,244...7,925,414
Ensembl chrNW_004955485:7,808,131...7,925,677
JBrowse link
BMP signaling pathway involved in spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrd chordin ISO (PMID:11472837) BHF-UCL PMID:11472837 NCBI chrNW_004955420:23,111,690...23,120,038
Ensembl chrNW_004955420:23,112,093...23,120,036
JBrowse link
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ift122 intraflagellar transport 122 ISO (MGI:4888042|PMID:21209331) BHF-UCL PMID:21209331 MGI:4888042 NCBI chrNW_004955429:17,795,757...17,858,609
Ensembl chrNW_004955429:17,794,879...17,858,609
JBrowse link
G Rfx4 regulatory factor X4 ISO (MGI:5430880|PMID:19887680) MGI PMID:19887680 MGI:5430880 NCBI chrNW_004955405:40,483,391...40,648,992
Ensembl chrNW_004955405:40,482,958...40,649,100
JBrowse link
G Tulp3 TUB like protein 3 ISO (MGI:3841503|PMID:19286674) MGI PMID:19286674 MGI:3841503 NCBI chrNW_004955429:18,424,912...18,484,522
Ensembl chrNW_004955429:18,453,311...18,482,400
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499
JBrowse link
G Gli3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chrNW_004955485:7,805,244...7,925,414
Ensembl chrNW_004955485:7,808,131...7,925,677
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499
JBrowse link
G Gli3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chrNW_004955485:7,805,244...7,925,414
Ensembl chrNW_004955485:7,808,131...7,925,677
JBrowse link
smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smo smoothened, frizzled class receptor ISO (MGI:4888042|PMID:21209331)
(MGI:3841503|PMID:19286674)
CACAO
MGI
PMID:19286674, PMID:21209331 MGI:3841503, MGI:4888042 NCBI chrNW_004955479:9,963,377...9,991,670
Ensembl chrNW_004955479:9,964,170...9,993,165
JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (MGI:3587461|PMID:16020526) UniProt PMID:16020526 MGI:3587461 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
G Dll4 delta like canonical Notch ligand 4 ISO (PMID:17728344) UniProtKB PMID:17728344 NCBI chrNW_004955416:7,807,049...7,816,346
Ensembl chrNW_004955416:7,807,049...7,817,420
JBrowse link
G Foxn4 forkhead box N4 ISO (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) UniProt PMID:16020526, PMID:17728344 MGI:3587461, MGI:3765356 NCBI chrNW_004955455:9,182,405...9,210,365
Ensembl chrNW_004955455:9,183,475...9,210,506
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 ISO (MGI:1334824|PMID:10217145) MGI PMID:10217145 MGI:1334824 NCBI chrNW_004955415:29,263,741...29,268,259
Ensembl chrNW_004955415:29,258,434...29,268,259
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 ISO (MGI:2136554|PMID:11239429) MGI PMID:11239429 MGI:2136554 NCBI chrNW_004955476:1,018,715...1,022,648
Ensembl chrNW_004955476:1,018,715...1,022,545
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 ISO (MGI:5435948|PMID:22932389) MGI PMID:22932389 MGI:5435948 NCBI chrNW_004955434:5,455,449...5,470,343
Ensembl chrNW_004955434:5,455,449...5,470,343
JBrowse link
G Lhx3 LIM homeobox 3 ISO (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chrNW_004955513:4,464,149...4,470,962
Ensembl chrNW_004955513:4,464,149...4,470,962
JBrowse link
G Shh sonic hedgehog signaling molecule ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    multicellular organismal process 6168
      pattern specification process 437
        regionalization 349
          spinal cord patterning 22
            spinal cord dorsal/ventral patterning 20
              BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
              retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
              smoothened signaling pathway involved in ventral spinal cord patterning + 7
              ventral spinal cord interneuron fate commitment + 11
Path 2
Term Annotations click to browse term
  biological_process 11892
    developmental process 5616
      anatomical structure development 5254
        multicellular organism development 4812
          system development 4532
            nervous system development 2347
              central nervous system development 1136
                spinal cord development 133
                  spinal cord patterning 22
                    spinal cord dorsal/ventral patterning 20
                      BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
                      negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
                      retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
                      smoothened signaling pathway involved in ventral spinal cord patterning + 7
                      ventral spinal cord interneuron fate commitment + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.