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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord dorsal/ventral patterning
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Accession:GO:0021513 term browser browse the term
Definition:The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms:exact_synonym: spinal cord dorsoventral patterning


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spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FUZ fuzzy planar cell polarity protein ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chr 6:54,823,680...54,830,425
Ensembl chr 6:54,823,666...54,829,508
JBrowse link
G GLI2 GLI family zinc finger 2 ISO (MGI:2154468|PMID:11748151)
(MGI:3612806|PMID:16364285)
(MGI:3051712|PMID:15215207)
MGI PMID:11748151, PMID:15215207, PMID:16364285 MGI:2154468, MGI:3051712, MGI:3612806 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306
JBrowse link
G GLI3 GLI family zinc finger 3 ISO (MGI:3612806|PMID:16364285)
(MGI:3051712|PMID:15215207)
MGI PMID:15215207, PMID:16364285 MGI:3051712, MGI:3612806 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,071...52,697,903
JBrowse link
G IFT88 intraflagellar transport 88 ISO (MGI:5052192|PMID:21761479) MGI PMID:21761479 MGI:5052192 NCBI chr11:943,444...1,025,617
Ensembl chr11:943,469...1,022,953
JBrowse link
G INTU inturned planar cell polarity protein IEA Ensembl GO_REF:0000107 NCBI chr 8:97,123,062...97,204,659
Ensembl chr 8:97,123,065...97,204,650
JBrowse link
G RAB23 RAB23, member RAS oncogene family ISO (MGI:3612806|PMID:16364285)
(MGI:3577662|PMID:15755804), (MGI:3612806|PMID:16364285)
(MGI:2679893|PMID:14603322)
MGI PMID:14603322, PMID:15755804, PMID:16364285 MGI:2679893, MGI:3577662, MGI:3612806 NCBI chr 7:28,632,065...28,658,958
Ensembl chr 7:28,632,082...28,658,953
JBrowse link
G SHH sonic hedgehog signaling molecule IEA Ensembl GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,718...2,555,484
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:3616741|PMID:16459298) MGI PMID:16459298 MGI:3616741 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,614,517
JBrowse link
BMP signaling pathway involved in spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRD chordin IEA Ensembl GO_REF:0000107 NCBI chr13:122,266,632...122,277,513
Ensembl chr13:122,266,615...122,277,509
JBrowse link
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFT122 intraflagellar transport 122 IEA Ensembl GO_REF:0000107 NCBI chr13:68,828,710...68,902,062
Ensembl chr13:68,828,705...68,902,062
JBrowse link
G RFX4 regulatory factor X4 ISO (MGI:5430880|PMID:19887680) MGI PMID:19887680 MGI:5430880 NCBI chr 5:13,590,845...13,758,913
Ensembl chr 5:13,590,851...13,926,604
JBrowse link
G TULP3 TUB like protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 5:67,201,680...67,238,348
Ensembl chr 5:67,199,446...67,238,324
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 IEA Ensembl GO_REF:0000107 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306
JBrowse link
G GLI3 GLI family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,071...52,697,903
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,614,517
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 IEA Ensembl GO_REF:0000107 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306
JBrowse link
G GLI3 GLI family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,071...52,697,903
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,614,517
JBrowse link
smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMO smoothened, frizzled class receptor IEA Ensembl GO_REF:0000107 NCBI chr18:19,450,730...19,478,796
Ensembl chr18:19,450,734...19,479,374
JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 ISO (MGI:3587461|PMID:16020526) UniProt PMID:16020526 MGI:3587461 NCBI chr 5:81,357,431...81,360,335 JBrowse link
G DLL4 delta like canonical Notch ligand 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:130,376,720...130,386,411
Ensembl chr 1:130,376,720...130,386,713
JBrowse link
G FOXN4 forkhead box N4 ISO (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) UniProt PMID:16020526, PMID:17728344 MGI:3587461, MGI:3765356 NCBI chr14:41,589,128...41,614,488 JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-2 NK2 homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr17:29,275,656...29,279,572
Ensembl chr17:29,275,682...29,278,606
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBX1 developing brain homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:39,229,392...39,234,304
Ensembl chr 2:39,229,356...39,234,969
JBrowse link
G DMRT3 doublesex and mab-3 related transcription factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 1:220,819,525...220,834,080
Ensembl chr 1:220,820,556...220,833,835
JBrowse link
G LHX3 LIM homeobox 3 IEA Ensembl GO_REF:0000107
G SHH sonic hedgehog signaling molecule ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,718...2,555,484
JBrowse link
G SOX1 SRY-box transcription factor 1 ISO (MGI:4834949|PMID:20844123) MGI PMID:20844123 MGI:4834949 NCBI chr11:77,985,771...77,989,383 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16548
    multicellular organismal process 8039
      pattern specification process 469
        regionalization 374
          spinal cord patterning 23
            spinal cord dorsal/ventral patterning 21
              BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
              retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
              smoothened signaling pathway involved in ventral spinal cord patterning + 7
              ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 16548
    developmental process 6302
      anatomical structure development 5842
        multicellular organism development 5340
          system development 4963
            nervous system development 2592
              central nervous system development 1218
                spinal cord development 141
                  spinal cord patterning 23
                    spinal cord dorsal/ventral patterning 21
                      BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
                      negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
                      retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning + 0
                      smoothened signaling pathway involved in ventral spinal cord patterning + 7
                      ventral spinal cord interneuron fate commitment + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.