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ONTOLOGY REPORT - ANNOTATIONS


Term:ventral spinal cord interneuron differentiation
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Accession:GO:0021514 term browser browse the term
Definition:The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Comment:This term was added by GO_REF:0000021.


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ventral spinal cord interneuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
RGD:1600115
G Lmo4 LIM domain only 4 JBrowse link 2 250,218,635 250,235,435 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Evx1 even-skipped homeobox 1 JBrowse link 4 82,370,829 82,374,313 RGD:1624291
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:1624291
RGD:1600115
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
G Dll4 delta like canonical Notch ligand 4 JBrowse link 3 111,135,011 111,146,746 RGD:1624291
RGD:1600115
G Foxn4 forkhead box N4 JBrowse link 12 48,101,012 48,121,281 RGD:1624291
RGD:1600115
ventral spinal cord interneuron fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbx1 developing brain homeobox 1 JBrowse link 1 104,969,218 104,973,648 RGD:1624291
RGD:1600115
G Dmrt3 doublesex and mab-3 related transcription factor 3 JBrowse link 1 243,589,607 243,602,926 RGD:1624291
RGD:1600115
G Lhx3 LIM homeobox 3 JBrowse link 3 3,653,861 3,662,509 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:8553789
G Sox1 SRY-box transcription factor 1 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      anatomical structure development 6063
        ventral spinal cord development 60
          ventral spinal cord interneuron differentiation 18
            ventral spinal cord interneuron fate commitment + 16
Path 2
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      anatomical structure development 6063
        multicellular organism development 5534
          system development 5081
            nervous system development 2592
              neurogenesis 1876
                generation of neurons 1741
                  neuron differentiation 1567
                    central nervous system neuron differentiation 235
                      ventral spinal cord interneuron differentiation 18
                        ventral spinal cord interneuron fate commitment + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.