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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord motor neuron cell fate specification
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Accession:GO:0021520 term browser browse the term
Definition:The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
Comment:This term was added by GO_REF:0000021.


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spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hoxc10 homeobox C10 JBrowse link 15 102,966,796 102,971,898 RGD:2290270
G Hoxd10 homeobox D10 JBrowse link 2 74,684,273 74,695,106 RGD:2290270
G Isl1 ISL1 transcription factor, LIM/homeodomain JBrowse link 13 116,298,270 116,309,688 RGD:2290270
G Isl2 insulin related protein 2 (islet 2) JBrowse link 9 55,538,677 55,547,667 RGD:2290270
G Lhx3 LIM homeobox protein 3 JBrowse link 2 26,200,212 26,208,249 RGD:2290270
G Mnx1 motor neuron and pancreas homeobox 1 JBrowse link 5 29,473,823 29,478,470 RGD:2290270
G Olig3 oligodendrocyte transcription factor 3 JBrowse link 10 19,356,539 19,358,604 RGD:2290270
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx6-1 NK6 homeobox 1 JBrowse link 5 101,659,184 101,664,711 RGD:2290270
G Nkx6-2 NK6 homeobox 2 JBrowse link 7 139,579,376 139,582,797 RGD:2290270
G Pax6 paired box 6 JBrowse link 2 105,668,896 105,698,410 RGD:2290270
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI-Kruppel family member GLI2 JBrowse link 1 118,834,061 119,054,405 RGD:2290270
G Gli3 GLI-Kruppel family member GLI3 JBrowse link 13 15,463,723 15,730,026 RGD:2290270
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 19 46,396,896 46,488,804 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23015
    cellular process 15767
      cellular developmental process 4446
        cell fate specification 104
          neuron fate specification 37
            spinal cord motor neuron cell fate specification 13
              regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 3
              smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
Path 2
Term Annotations click to browse term
  biological_process 23015
    developmental process 6306
      anatomical structure development 5847
        multicellular organism development 5339
          system development 4730
            nervous system development 2347
              neurogenesis 1792
                generation of neurons 1682
                  neuron differentiation 1503
                    neuron fate commitment 79
                      neuron fate specification 37
                        spinal cord motor neuron cell fate specification 13
                          regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 3
                          smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.