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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord motor neuron cell fate specification
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Accession:GO:0021520 term browser browse the term
Definition:The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
Comment:This term was added by GO_REF:0000021.


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spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hoxc10 homeo box C10 JBrowse link 7 144,577,578 144,582,802 RGD:1624291
RGD:1600115
G Hoxd10 homeo box D10 JBrowse link 3 61,614,133 61,617,342 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
G Isl2 ISL LIM homeobox 2 JBrowse link 8 60,117,565 60,122,716 RGD:1624291
RGD:1600115
G Lhx3 LIM homeobox 3 JBrowse link 3 3,653,861 3,662,509 RGD:1624291
RGD:1600115
G Mnx1 motor neuron and pancreas homeobox 1 JBrowse link 4 2,376,350 2,381,308 RGD:1624291
RGD:13792537
G Olig3 oligodendrocyte transcription factor 3 JBrowse link 1 14,797,766 14,799,835 RGD:1624291
RGD:1600115
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:1624291
RGD:1600115
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    cellular process 17226
      cellular developmental process 4428
        cell fate specification 104
          neuron fate specification 37
            spinal cord motor neuron cell fate specification 13
              regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 3
              smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
Path 2
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      anatomical structure development 6113
        multicellular organism development 5583
          system development 5101
            nervous system development 2597
              neurogenesis 1882
                generation of neurons 1747
                  neuron differentiation 1574
                    neuron fate commitment 78
                      neuron fate specification 37
                        spinal cord motor neuron cell fate specification 13
                          regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 3
                          smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.