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ONTOLOGY REPORT - ANNOTATIONS


Term:ventral spinal cord interneuron specification
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Accession:GO:0021521 term browser browse the term
Definition:The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.


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ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBX1 developing brain homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr11:20,156,155...20,160,475
Ensembl chr11:20,156,155...20,160,475
JBrowse link
G DMRT3 doublesex and mab-3 related transcription factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:976,655...991,732
Ensembl chr 9:976,655...991,732
JBrowse link
G LHX3 LIM homeobox 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128
JBrowse link
G SHH sonic hedgehog signaling molecule ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SOX1 SRY-box transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr13:112,067,149...112,071,706
Ensembl chr13:112,067,149...112,071,706
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 ISS UniProtKB GO_REF:0000024 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653
JBrowse link
G GLI3 GLI family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr 7:41,960,949...42,237,209
Ensembl chr 7:41,960,949...42,237,870
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr10:102,502,801...102,633,535
Ensembl chr10:102,503,987...102,633,535
Ensembl chr10:102,503,987...102,633,535
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    cellular process 17690
      cellular developmental process 4995
        cell fate specification 104
          cell fate specification involved in pattern specification 8
            ventral spinal cord interneuron specification 8
              retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification 0
              smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
Path 2
Term Annotations click to browse term
  biological_process 18672
    developmental process 7466
      anatomical structure development 6873
        multicellular organism development 6346
          system development 5749
            nervous system development 2886
              neurogenesis 1984
                generation of neurons 1839
                  neuron differentiation 1676
                    central nervous system neuron differentiation 248
                      ventral spinal cord interneuron differentiation 14
                        ventral spinal cord interneuron fate commitment 12
                          ventral spinal cord interneuron specification 8
                            retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification 0
                            smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.