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ONTOLOGY REPORT - ANNOTATIONS


Term:ventral spinal cord interneuron specification
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Accession:GO:0021521 term browser browse the term
Definition:The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.


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ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 IMP (MGI:2136554|PMID:11239429) MGI PMID:11239429 MGI:2136554 NCBI chr 7:49,631,499...49,636,835
Ensembl chr 7:49,631,499...49,636,849
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 IMP (MGI:5435948|PMID:22932389) MGI PMID:22932389 MGI:5435948 NCBI chr19:25,610,246...25,623,921
Ensembl chr19:25,610,301...25,623,921
JBrowse link
G Lhx3 LIM homeobox protein 3 IDA (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chr 2:26,200,212...26,208,249
Ensembl chr 2:26,200,212...26,208,289
JBrowse link
G Shh sonic hedgehog ISO MGI GO_REF:0000008, MGI:2154458 NCBI chr 5:28,456,840...28,467,101
Ensembl chr 5:28,456,815...28,467,256
JBrowse link
G Sox1 SRY (sex determining region Y)-box 1 IMP (MGI:4834949|PMID:20844123) MGI PMID:20844123 MGI:4834949 NCBI chr 8:12,395,519...12,399,555
Ensembl chr 8:12,395,295...12,400,126
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI-Kruppel family member GLI2 IGI (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr 1:118,834,061...119,054,405
Ensembl chr 1:118,834,132...119,053,619
JBrowse link
G Gli3 GLI-Kruppel family member GLI3 IGI (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr13:15,463,723...15,730,026
Ensembl chr13:15,463,235...15,730,026
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling IMP (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr19:46,396,896...46,488,804
Ensembl chr19:46,396,896...46,488,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23387
    cellular process 17460
      cellular developmental process 4667
        cell fate specification 102
          cell fate specification involved in pattern specification 8
            ventral spinal cord interneuron specification 8
              retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification 0
              smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
Path 2
Term Annotations click to browse term
  biological_process 23387
    developmental process 7031
      anatomical structure development 6505
        multicellular organism development 5969
          system development 5380
            nervous system development 2722
              neurogenesis 1939
                generation of neurons 1785
                  neuron differentiation 1618
                    central nervous system neuron differentiation 245
                      ventral spinal cord interneuron differentiation 14
                        ventral spinal cord interneuron fate commitment 12
                          ventral spinal cord interneuron specification 8
                            retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification 0
                            smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.