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ONTOLOGY REPORT - ANNOTATIONS


Term:cranial nerve morphogenesis
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Accession:GO:0021602 term browser browse the term
Definition:The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


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cranial nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO MGI:MGI:2179740 (MGI:MGI:2179743|PMID:11694877) RGD PMID:11694877 MGI:MGI:2179743 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Plxna4 plexin A4 ISO MGI:MGI:3578655 (MGI:MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
abducens nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa1 homeobox A1 ISO (PMID:16155570) RGD PMID:16155570 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Mafb MAF bZIP transcription factor B ISO
ISS
(MGI:MGI:5816405|PMID:27181683)
GO_REF:0000024
RGD
UniProt
PMID:27181683 GO_REF:0000024, MGI:MGI:5816405 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
facial nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adarb1 adenosine deaminase, RNA-specific, B1 ISO
IEA
MGI:MGI:4840554 (MGI:MGI:4831065|PMID:20826656)
GO_REF:0000107
RGD
Ensembl
PMID:20826656 GO_REF:0000107, MGI:MGI:4831065 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Plxna4 plexin A4 ISO MGI:MGI:3578655 (MGI:MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
G Six1 SIX homeobox 1 ISO MGI:MGI:2655195 (MGI:MGI:2671031|PMID:12874121) RGD PMID:12874121 MGI:MGI:2671031 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
facial nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr2 early growth response 2 ISS
ISO
GO_REF:0000024
MGI:MGI:96170 (MGI:MGI:1306866|PMID:9806922), (MGI:MGI:1331140|PMID:10068633), (MGI:MGI:69122|PMID:7935840)
UniProt
RGD
PMID:7935840, PMID:9806922, PMID:10068633 GO_REF:0000024, MGI:MGI:1306866, MGI:MGI:1331140, MGI:MGI:69122 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Hoxa1 homeobox A1 ISO MGI:MGI:95296 (MGI:MGI:1306866|PMID:9806922) RGD PMID:9806922 MGI:MGI:1306866 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Hoxb1 homeo box B1 ISO MGI:MGI:1857824 (MGI:MGI:83677|PMID:8898234) RGD PMID:8898234 MGI:MGI:83677 NCBI chr10:84,214,358...84,215,812
Ensembl chr10:84,214,358...84,215,687
JBrowse link
G Hoxb2 homeobox B2 ISO MGI:MGI:2151772 (MGI:MGI:85074|PMID:9012503) RGD PMID:9012503 MGI:MGI:85074 NCBI chr10:84,200,859...84,203,065
Ensembl chr10:84,200,880...84,202,688
JBrowse link
G Nrp1 neuropilin 1 ISO (MGI:MGI:3788968|PMID:18356247), (MGI:MGI:3822054|PMID:18804103) RGD PMID:18356247, PMID:18804103 MGI:MGI:3788968, MGI:MGI:3822054 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nrp2 neuropilin 2 ISO (MGI:MGI:3788968|PMID:18356247) RGD PMID:18356247 MGI:MGI:3788968 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087
JBrowse link
G Plxna3 plexin A3 ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr  X:156,363,400...156,379,433
Ensembl chr  X:156,363,405...156,379,189
JBrowse link
G Plxna4 plexin A4 ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
G Sema3a semaphorin 3A ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sema3f semaphorin 3F ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
JBrowse link
glossopharyngeal nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa3 homeobox A3 ISO MGI:MGI:1857992|MGI:MGI:96184|MGI:MGI:96207 (MGI:MGI:1195045|PMID:9441667) RGD PMID:9441667 MGI:MGI:1195045 NCBI chr 4:82,137,802...82,181,836
Ensembl chr 4:82,138,683...82,141,385
JBrowse link
G Hoxb3 homeo box B3 ISO MGI:MGI:96175|MGI:MGI:96207 (MGI:MGI:1195045|PMID:9441667) RGD PMID:9441667 MGI:MGI:1195045 NCBI chr10:84,170,629...84,196,823
Ensembl chr10:84,182,118...84,195,796
JBrowse link
G Hoxd3 homeo box D3 ISO
IEA
MGI:MGI:96175|MGI:MGI:96184 (MGI:MGI:1195045|PMID:9441667)
GO_REF:0000107
RGD
Ensembl
PMID:9441667 GO_REF:0000107, MGI:MGI:1195045 NCBI chr 3:61,650,569...61,670,285
Ensembl chr 3:61,658,245...61,670,282
JBrowse link
G Plxna4 plexin A4 ISO MGI:MGI:3578655 (MGI:MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
hypoglossal nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adarb1 adenosine deaminase, RNA-specific, B1 ISO
IEA
MGI:MGI:4840554 (MGI:MGI:4831065|PMID:20826656)
GO_REF:0000107
RGD
Ensembl
PMID:20826656 GO_REF:0000107, MGI:MGI:4831065 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
oculomotor nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phox2a paired-like homeobox 2a ISO
IEA
(MGI:MGI:1098916|PMID:9374403)
GO_REF:0000107
RGD
Ensembl
PMID:9374403 GO_REF:0000107, MGI:MGI:1098916 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO
ISS
(MGI:MGI:80519|PMID:8622766)
GO_REF:0000024
RGD
UniProt
PMID:8622766 GO_REF:0000024, MGI:MGI:80519 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
olfactory nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmd dystrophin ISO MGI:MGI:3531484 (MGI:MGI:3805594|PMID:18586242) RGD PMID:18586242 MGI:MGI:3805594 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
optic nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:MGI:1926253|MGI:MGI:2158714 (MGI:MGI:2181503|PMID:11344259), (MGI:MGI:3721829|PMID:12097474) RGD PMID:11344259, PMID:12097474 MGI:MGI:2181503, MGI:MGI:3721829 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Ephb1 Eph receptor B1 ISO MGI:MGI:2677305 (MGI:MGI:2675767|PMID:12971893) RGD PMID:12971893 MGI:MGI:2675767 NCBI chr 8:110,376,954...110,813,193
Ensembl chr 8:110,376,954...110,813,000
JBrowse link
G Ephb2 Eph receptor B2 ISO MGI:MGI:2149765 (MGI:MGI:2675767|PMID:12971893) RGD PMID:12971893 MGI:MGI:2675767 NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456
JBrowse link
G Gli3 GLI family zinc finger 3 ISO MGI:MGI:1856276 (MGI:MGI:3617688|PMID:16342201) RGD PMID:16342201 MGI:MGI:3617688 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:84247|PMID:8951055)
GO_REF:0000024
RGD
UniProt
PMID:8951055 GO_REF:0000024, MGI:MGI:84247 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
optic nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna2 potassium voltage-gated channel subfamily A member 2 ISO MGI:MGI:3043422 (MGI:MGI:3042560|PMID:15102918) RGD PMID:15102918 MGI:MGI:3042560 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:84247|PMID:8951055)
GO_REF:0000024
RGD
UniProt
PMID:8951055 GO_REF:0000024, MGI:MGI:84247 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
positive regulation of optic nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:5009386|PMID:18083586)
GO_REF:0000024
RGD
UniProt
PMID:18083586 GO_REF:0000024, MGI:MGI:5009386 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
trigeminal nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 ISO MGI:MGI:1857853 (MGI:MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:MGI:3578029 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Plxna4 plexin A4 ISO MGI:MGI:3578655 (MGI:MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
trigeminal nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Plxna3 plexin A3 ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr  X:156,363,400...156,379,433
Ensembl chr  X:156,363,405...156,379,189
JBrowse link
G Plxna4 plexin A4 ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
G Sema3a semaphorin 3A ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sema3f semaphorin 3F ISO (MGI:MGI:3822054|PMID:18804103) RGD PMID:18804103 MGI:MGI:3822054 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
JBrowse link
trochlear nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phox2a paired-like homeobox 2a ISO
IEA
(MGI:MGI:1098916|PMID:9374403)
GO_REF:0000107
RGD
Ensembl
PMID:9374403 GO_REF:0000107, MGI:MGI:1098916 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
vagus nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plxna4 plexin A4 ISO MGI:MGI:3578655 (MGI:MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
G Tbx1 T-box transcription factor 1 ISO
ISS
MGI:MGI:2179136 (MGI:MGI:4948210|PMID:20939858)
GO_REF:0000024
RGD
UniProt
PMID:20939858 GO_REF:0000024, MGI:MGI:4948210 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
vestibulocochlear nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp8b1 ATPase phospholipid transporting 8B1 ISO (MGI:MGI:3849653|PMID:19478059) RGD PMID:19478059 MGI:MGI:3849653 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Neurog1 neurogenin 1 ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:9,154,656...9,156,175
Ensembl chr17:9,154,656...9,156,175
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:84247|PMID:8951055)
GO_REF:0000024
RGD
UniProt
PMID:8951055 GO_REF:0000024, MGI:MGI:84247 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Tifab TIFA inhibitor ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:9,234,948...9,239,266
Ensembl chr17:9,236,249...9,239,265
JBrowse link
vestibulocochlear nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 ISO (MGI:MGI:3788968|PMID:18356247) RGD PMID:18356247 MGI:MGI:3788968 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nrp2 neuropilin 2 ISO (MGI:MGI:3788968|PMID:18356247) RGD PMID:18356247 MGI:MGI:3788968 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure morphogenesis 2872
        cranial nerve morphogenesis 30
          abducens nerve morphogenesis + 2
          accessory nerve morphogenesis + 0
          cranial ganglion morphogenesis + 0
          cranial nerve formation + 8
          cranial nerve structural organization + 13
          facial nerve morphogenesis + 12
          glossopharyngeal nerve morphogenesis + 4
          hypoglossal nerve morphogenesis + 1
          oculomotor nerve morphogenesis + 2
          olfactory nerve morphogenesis + 1
          optic nerve morphogenesis + 6
          trigeminal nerve morphogenesis + 5
          trochlear nerve morphogenesis + 1
          vagus nerve morphogenesis + 2
          vestibulocochlear nerve morphogenesis + 6
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            nervous system development 2716
              nerve development 91
                cranial nerve development 57
                  cranial nerve morphogenesis 30
                    abducens nerve morphogenesis + 2
                    accessory nerve morphogenesis + 0
                    cranial ganglion morphogenesis + 0
                    cranial nerve formation + 8
                    cranial nerve structural organization + 13
                    facial nerve morphogenesis + 12
                    glossopharyngeal nerve morphogenesis + 4
                    hypoglossal nerve morphogenesis + 1
                    oculomotor nerve morphogenesis + 2
                    olfactory nerve morphogenesis + 1
                    optic nerve morphogenesis + 6
                    trigeminal nerve morphogenesis + 5
                    trochlear nerve morphogenesis + 1
                    vagus nerve morphogenesis + 2
                    vestibulocochlear nerve morphogenesis + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.