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ONTOLOGY REPORT - ANNOTATIONS


Term:cranial nerve formation
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Accession:GO:0021603 term browser browse the term
Definition:The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


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abducens nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa1 homeobox A1 ISO (PMID:16155570) RGD PMID:16155570 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Mafb MAF bZIP transcription factor B ISO
ISS
(MGI:MGI:5816405|PMID:27181683)
GO_REF:0000024
RGD
UniProt
PMID:27181683 GO_REF:0000024, MGI:MGI:5816405 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
oculomotor nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phox2a paired-like homeobox 2a ISO
IEA
(MGI:MGI:1098916|PMID:9374403)
GO_REF:0000107
RGD
Ensembl
PMID:9374403 GO_REF:0000107, MGI:MGI:1098916 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO
ISS
(MGI:MGI:80519|PMID:8622766)
GO_REF:0000024
RGD
UniProt
PMID:8622766 GO_REF:0000024, MGI:MGI:80519 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
positive regulation of optic nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:5009386|PMID:18083586)
GO_REF:0000024
RGD
UniProt
PMID:18083586 GO_REF:0000024, MGI:MGI:5009386 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
trochlear nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phox2a paired-like homeobox 2a ISO
IEA
(MGI:MGI:1098916|PMID:9374403)
GO_REF:0000107
RGD
Ensembl
PMID:9374403 GO_REF:0000107, MGI:MGI:1098916 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
vestibulocochlear nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp8b1 ATPase phospholipid transporting 8B1 ISO (MGI:MGI:3849653|PMID:19478059) RGD PMID:19478059 MGI:MGI:3849653 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Neurog1 neurogenin 1 ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:9,154,656...9,156,175
Ensembl chr17:9,154,656...9,156,175
JBrowse link
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:84247|PMID:8951055)
GO_REF:0000024
RGD
UniProt
PMID:8951055 GO_REF:0000024, MGI:MGI:84247 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Tifab TIFA inhibitor ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:9,234,948...9,239,266
Ensembl chr17:9,236,249...9,239,265
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure formation involved in morphogenesis 1213
        cranial nerve formation 8
          abducens nerve formation 2
          accessory nerve formation 0
          facial nerve formation 0
          glossopharyngeal nerve formation 0
          hypoglossal nerve formation 0
          oculomotor nerve formation 2
          olfactory nerve formation 0
          optic nerve formation + 1
          trigeminal nerve formation 0
          trochlear nerve formation 1
          vagus nerve formation 0
          vestibulocochlear nerve formation 4
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              nerve development 91
                cranial nerve development 57
                  cranial nerve morphogenesis 30
                    cranial nerve formation 8
                      abducens nerve formation 2
                      accessory nerve formation 0
                      facial nerve formation 0
                      glossopharyngeal nerve formation 0
                      hypoglossal nerve formation 0
                      oculomotor nerve formation 2
                      olfactory nerve formation 0
                      optic nerve formation + 1
                      trigeminal nerve formation 0
                      trochlear nerve formation 1
                      vagus nerve formation 0
                      vestibulocochlear nerve formation 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.