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ONTOLOGY REPORT - ANNOTATIONS


Term:central nervous system maturation
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Accession:GO:0021626 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


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central nervous system maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 ISO
ISS
(PMID:30985297)
GO_REF:0000024
RGD
UniProt
PMID:30985297 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO (MGI:MGI:5576986|PMID:24487234) RGD PMID:24487234 MGI:MGI:5576986 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
cerebellar granular layer maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cend1 cell cycle exit and neuronal differentiation 1 ISO
IBA
MGI:MGI:4831137 (MGI:MGI:4830814|PMID:20153830)
PMID:21873635
RGD PMID:20153830, PMID:21873635 MGI:MGI:4830814, RGD:13792537 NCBI chr 1:214,407,072...214,410,069
Ensembl chr 1:214,408,100...214,408,549
JBrowse link
G LOC100911402 cell cycle exit and neuronal differentiation protein 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,970,163...213,973,224
Ensembl chr 1:213,970,174...213,973,163
JBrowse link
cerebellar Purkinje cell layer maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arcn1 archain 1 ISO MGI:MGI:2671790 (MGI:MGI:4454933|PMID:20502676) RGD PMID:20502676 MGI:MGI:4454933 NCBI chr 8:49,051,257...49,075,861
Ensembl chr 8:49,051,246...49,075,892
JBrowse link
G Rere arginine-glutamic acid dipeptide repeats ISO MGI:MGI:3577419 (MGI:MGI:5582020|PMID:24466353) RGD PMID:24466353 MGI:MGI:5582020 NCBI chr 5:167,330,966...167,664,506
Ensembl chr 5:167,331,035...167,664,505
JBrowse link
cerebellum maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO
IEA
MGI:MGI:2180190 (MGI:MGI:2179541|PMID:11344116)
GO_REF:0000107
RGD
Ensembl
PMID:11344116 GO_REF:0000107, MGI:MGI:2179541 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
pons maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO
IEA
MGI:MGI:1928270 (MGI:MGI:65431|PMID:8313466)
GO_REF:0000107
RGD
Ensembl
PMID:8313466 GO_REF:0000107, MGI:MGI:65431 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
superior olivary nucleus maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 ISO MGI:MGI:1330828 (MGI:MGI:2149271|PMID:11517264) RGD PMID:11517264 MGI:MGI:2149271 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 ISO MGI:MGI:101764 (MGI:MGI:2149271|PMID:11517264) RGD PMID:11517264 MGI:MGI:2149271 NCBI chr 9:82,120,059...82,121,527
Ensembl chr 9:82,120,059...82,121,527
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      developmental maturation 340
        anatomical structure maturation 286
          central nervous system maturation 10
            hindbrain maturation + 8
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              central nervous system development 1262
                central nervous system maturation 10
                  hindbrain maturation + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.