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ONTOLOGY REPORT - ANNOTATIONS


Term:optic nerve morphogenesis
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Accession:GO:0021631 term browser browse the term
Definition:The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
Synonyms:related_synonym: CN II morphogenesis


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optic nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit IEA Ensembl GO_REF:0000107 NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722
JBrowse link
G EPHB1 EPH receptor B1 IEA Ensembl GO_REF:0000107 NCBI chr23:31,485,701...31,918,754
Ensembl chr23:31,485,534...31,917,393
JBrowse link
G EPHB2 EPH receptor B2 IEA Ensembl GO_REF:0000107 NCBI chr 2:76,427,112...76,551,494
Ensembl chr 2:76,428,203...76,612,786
JBrowse link
G GLI3 GLI family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132
JBrowse link
G PAX2 paired box 2 ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
optic nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA2 potassium voltage-gated channel subfamily A member 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:41,405,453...41,415,727
Ensembl chr 6:41,407,070...41,408,823
JBrowse link
G PAX2 paired box 2 ISO (MGI:84247|PMID:8951055) DFLAT PMID:8951055 MGI:84247 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link
positive regulation of optic nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 ISO (MGI:5009386|PMID:18083586) UniProt PMID:18083586 MGI:5009386 NCBI chr28:13,442,894...13,519,853
Ensembl chr28:13,442,893...13,532,094
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    developmental process 6310
      anatomical structure morphogenesis 2785
        cranial nerve morphogenesis 30
          optic nerve morphogenesis 6
            optic nerve formation + 1
            optic nerve structural organization 2
Path 2
Term Annotations click to browse term
  biological_process 16190
    developmental process 6310
      anatomical structure development 5858
        multicellular organism development 5351
          system development 4984
            nervous system development 2586
              nerve development 89
                cranial nerve development 56
                  optic nerve development 16
                    optic nerve morphogenesis 6
                      optic nerve formation + 1
                      optic nerve structural organization 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.