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ONTOLOGY REPORT - ANNOTATIONS


Term:optic nerve morphogenesis
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Accession:GO:0021631 term browser browse the term
Definition:The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
Synonyms:related_synonym: CN II morphogenesis


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optic nerve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISS UniProtKB GO_REF:0000024 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013
JBrowse link
G EPHB1 EPH receptor B1 IEA Ensembl GO_REF:0000107 NCBI chr 3:134,595,264...135,260,467
Ensembl chr 3:134,597,801...135,260,467
JBrowse link
G EPHB2 EPH receptor B2 IEA Ensembl GO_REF:0000107 NCBI chr 1:22,710,770...22,921,500
Ensembl chr 1:22,710,839...22,921,500
JBrowse link
G GLI3 GLI family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr 7:41,960,949...42,237,209
Ensembl chr 7:41,960,949...42,237,870
JBrowse link
G PAX2 paired box 2 ISS UniProtKB GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,603...100,829,941
Ensembl chr10:100,735,603...100,829,941
JBrowse link
optic nerve structural organization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNA2 potassium voltage-gated channel subfamily A member 2 ISO (MGI:3042560|PMID:15102918) MGI PMID:15102918 MGI:3042560 NCBI chr 1:110,593,580...110,631,536
Ensembl chr 1:110,519,837...110,631,474
JBrowse link
G PAX2 paired box 2 ISS UniProtKB GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,603...100,829,941
Ensembl chr10:100,735,603...100,829,941
JBrowse link
positive regulation of optic nerve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX2 paired box 2 ISS UniProtKB GO_REF:0000024 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,603...100,829,941
Ensembl chr10:100,735,603...100,829,941
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    developmental process 7466
      anatomical structure morphogenesis 3097
        cranial nerve morphogenesis 31
          optic nerve morphogenesis 6
            optic nerve formation + 1
            optic nerve structural organization 2
Path 2
Term Annotations click to browse term
  biological_process 18672
    developmental process 7466
      anatomical structure development 6873
        multicellular organism development 6346
          system development 5749
            nervous system development 2886
              nerve development 93
                cranial nerve development 58
                  optic nerve development 16
                    optic nerve morphogenesis 6
                      optic nerve formation + 1
                      optic nerve structural organization 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.