ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar Purkinje cell layer development
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Accession:GO:0021680 term browser browse the term
Definition:The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
Comment:This term was added by GO_REF:0000021.


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cerebellar Purkinje cell layer development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aars alanyl-tRNA synthetase JBrowse link 19 43,193,264 43,215,281 RGD:1624291
RGD:1600115
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
G B4galt2 beta-1,4-galactosyltransferase 2 JBrowse link 5 136,707,510 136,717,345 RGD:1624291
RGD:1600115
G Cacna1a calcium voltage-gated channel subunit alpha1 A JBrowse link 19 25,453,236 25,749,550 RGD:1624291
G Faim2 Fas apoptotic inhibitory molecule 2 JBrowse link 7 141,158,769 141,185,781 RGD:1624291
RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1624291
RGD:1600115
G Klhl1 kelch-like family member 1 JBrowse link 15 80,270,846 80,714,176 RGD:1624291
G Myh10 myosin heavy chain 10 JBrowse link 10 55,274,910 55,406,738 RGD:1624291
RGD:1600115
G Naglu N-acetyl-alpha-glucosaminidase JBrowse link 10 88,979,363 88,986,879 RGD:1624291
RGD:1600115
G Nf1x nuclear factor 1 X JBrowse link 19 25,818,640 25,914,777 RGD:1624291
G Sez6 seizure related 6 homolog JBrowse link 10 64,865,802 64,915,461 RGD:1624291
RGD:1600115
G Sez6l seizure related 6 homolog like JBrowse link 12 50,090,345 50,243,020 RGD:1624291
RGD:1600115
G Sez6l2 seizure related 6 homolog like 2 JBrowse link 1 198,383,201 198,403,544 RGD:1624291
RGD:1600115
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII JBrowse link 10 38,779,132 38,782,489 RGD:1624291
RGD:1600115
cerebellar Purkinje cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtpbp1 ATP/GTP binding protein 1 JBrowse link 17 5,510,009 5,614,416 RGD:1600115
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 JBrowse link 4 145,704,779 145,948,997 RGD:1624291
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Atxn2 ataxin 2 JBrowse link 12 40,264,601 40,335,637 RGD:1624291
G Cacna1a calcium voltage-gated channel subunit alpha1 A JBrowse link 19 25,453,236 25,749,550 RGD:1600115
RGD:1624291
G Cend1 cell cycle exit and neuronal differentiation 1 JBrowse link 1 214,407,072 214,410,069 RGD:1624291
RGD:13792537
G Faim2 Fas apoptotic inhibitory molecule 2 JBrowse link 7 141,158,769 141,185,781 RGD:1624291
RGD:1600115
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 JBrowse link 8 72,029,550 72,198,363 RGD:1624291
RGD:1600115
G Ldb1 LIM domain binding 1 JBrowse link 1 265,772,729 265,798,442 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Lhx5 LIM homeobox 5 JBrowse link 12 41,663,000 41,671,437 RGD:1624291
RGD:1600115
G LOC100911402 cell cycle exit and neuronal differentiation protein 1-like JBrowse link 1 213,970,163 213,973,224 RGD:13792537
G Rora RAR-related orphan receptor A JBrowse link 8 75,515,886 75,616,477 RGD:1624291
RGD:1600115
G Skor2 SKI family transcriptional corepressor 2 JBrowse link 18 73,145,596 73,199,395 RGD:1624291
RGD:1600115
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:8693630
cerebellar Purkinje cell layer formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Whrn whirlin JBrowse link 5 79,235,541 79,317,206 RGD:1624291
RGD:1600115
cerebellar Purkinje cell layer maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arcn1 archain 1 JBrowse link 8 49,051,257 49,075,861 RGD:1624291
RGD:1600115
G Rere arginine-glutamic acid dipeptide repeats JBrowse link 5 167,330,966 167,664,506 RGD:1624291
RGD:1600115
cerebellar Purkinje cell layer morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 JBrowse link 4 145,704,779 145,948,997 RGD:1624291
G Coq8b coenzyme Q8B JBrowse link 1 84,043,487 84,067,066 RGD:1624291
RGD:1600115
G Sptbn2 spectrin, beta, non-erythrocytic 2 JBrowse link 1 219,964,429 220,006,811 RGD:1624291
RGD:1600115
cerebellar Purkinje cell layer structural organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Kif14 kinesin family member 14 JBrowse link 13 53,350,073 53,421,992 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        cerebellar Purkinje cell layer development 34
          cerebellar Purkinje cell layer maturation 2
          cerebellar Purkinje cell layer morphogenesis + 20
Path 2
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        multicellular organism development 5423
          system development 5002
            nervous system development 2549
              central nervous system development 1154
                brain development 890
                  hindbrain development 210
                    metencephalon development 161
                      cerebellum development 149
                        cerebellar cortex development 64
                          cerebellar Purkinje cell layer development 34
                            cerebellar Purkinje cell layer maturation 2
                            cerebellar Purkinje cell layer morphogenesis + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.