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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer formation
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Accession:GO:0021684 term browser browse the term
Definition:The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granule cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 ISO MGI:1857876 (MGI:1275896|PMID:9668038) RGD PMID:9668038 MGI:1275896 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Cbln1 cerebellin 1 precursor ISS
ISO
GO_REF:0000024
UniProtKB:Q61625 (MGI:4839424|PMID:20537373)
BHF-UCL
RGD
PMID:20537373 GO_REF:0000024, MGI:4839424 NCBI chr19:20,607,507...20,611,316
Ensembl chr19:20,607,507...20,611,316
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 IEA
ISO
ISS
GO_REF:0000107
UniProtKB:Q9R171 (MGI:4839424|PMID:20537373)
GO_REF:0000024
Ensembl
RGD
BHF-UCL
PMID:20537373 GO_REF:0000024, GO_REF:0000107, MGI:4839424 NCBI chr 4:94,068,112...95,476,864
Ensembl chr 4:94,696,965...95,442,778
JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 ISO (MGI:3769586|PMID:17984326) RGD PMID:17984326 MGI:3769586 NCBI chr 1:212,229,751...212,279,254
Ensembl chr 1:212,230,259...212,277,694
JBrowse link
G Mtpn myotrophin IEP RGD PMID:8144589 RGD:632797 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link
G Nfix nuclear factor I X ISO MGI:3802571 (MGI:5436217|PMID:21800304) RGD PMID:21800304 MGI:5436217 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nrxn1 neurexin 1 ISS
ISO
GO_REF:0000024
UniProtKB:Q61625|UniProtKB:Q9R171 (MGI:4839424|PMID:20537373)
BHF-UCL
RGD
PMID:20537373 GO_REF:0000024, MGI:4839424 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Ophn1 oligophrenin 1 ISO (PMID:27160703) RGD PMID:27160703 NCBI chr  X:68,185,865...68,579,518
Ensembl chr  X:68,189,161...68,563,137
JBrowse link
G Prox1 prospero homeobox 1 ISO (MGI:4849596|PMID:20808958) RGD PMID:20808958 MGI:4849596 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Top2a DNA topoisomerase II alpha IEP RGD PMID:11170002 RGD:8693630 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 ISO (MGI:1351063|PMID:10624947) RGD PMID:10624947 MGI:1351063 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Wnt7a Wnt family member 7A ISO (MGI:1195230|PMID:9405095) RGD PMID:9405095 MGI:1195230 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure formation involved in morphogenesis 1214
        cerebellar granular layer formation 12
          cerebellar Golgi cell differentiation 0
          cerebellar granule cell differentiation 12
          cerebellar unipolar brush cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            nervous system development 2719
              central nervous system development 1260
                brain development 965
                  hindbrain development 218
                    metencephalon development 167
                      cerebellum development 155
                        cerebellar cortex development 69
                          cerebellar granular layer development 19
                            cerebellar granular layer morphogenesis 14
                              cerebellar granular layer formation 12
                                cerebellar Golgi cell differentiation 0
                                cerebellar granule cell differentiation 12
                                cerebellar unipolar brush cell differentiation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.