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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer maturation
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Accession:GO:0021686 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cend1 cell cycle exit and neuronal differentiation 1 ISO
IBA
MGI:MGI:4831137 (MGI:MGI:4830814|PMID:20153830)
PMID:21873635
RGD PMID:20153830, PMID:21873635 MGI:MGI:4830814, RGD:13792537 NCBI chr 1:214,407,072...214,410,069
Ensembl chr 1:214,408,100...214,408,549
JBrowse link
G LOC100911402 cell cycle exit and neuronal differentiation protein 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,970,163...213,973,224
Ensembl chr 1:213,970,174...213,973,163
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        anatomical structure maturation 286
          cerebellar granular layer maturation 2
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              central nervous system development 1262
                brain development 966
                  hindbrain development 218
                    metencephalon development 167
                      cerebellum development 155
                        cerebellar cortex development 69
                          cerebellar granular layer development 19
                            cerebellar granular layer maturation 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.