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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar Purkinje cell layer maturation
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Accession:GO:0021691 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


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cerebellar Purkinje cell layer maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arcn1 archain 1 ISO MGI:MGI:2671790 (MGI:MGI:4454933|PMID:20502676) RGD PMID:20502676 MGI:MGI:4454933 NCBI chr 8:49,051,257...49,075,861
Ensembl chr 8:49,051,246...49,075,892
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G Rere arginine-glutamic acid dipeptide repeats ISO MGI:MGI:3577419 (MGI:MGI:5582020|PMID:24466353) RGD PMID:24466353 MGI:MGI:5582020 NCBI chr 5:167,330,966...167,664,506
Ensembl chr 5:167,331,035...167,664,505
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        anatomical structure maturation 286
          cerebellar Purkinje cell layer maturation 2
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            nervous system development 2722
              central nervous system development 1262
                brain development 966
                  hindbrain development 218
                    metencephalon development 167
                      cerebellum development 155
                        cerebellar cortex development 69
                          cerebellar Purkinje cell layer development 39
                            cerebellar Purkinje cell layer maturation 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.