ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar Purkinje cell layer maturation
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Accession:GO:0021691 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
Comment:This term was added by GO_REF:0000021.


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cerebellar Purkinje cell layer maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arcn1 archain 1 JBrowse link 8 49,051,257 49,075,861 RGD:1624291
RGD:1600115
G Rere arginine-glutamic acid dipeptide repeats JBrowse link 5 167,330,966 167,664,506 RGD:1624291
RGD:1600115

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  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        anatomical structure maturation 198
          cerebellar Purkinje cell layer maturation 2
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  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        multicellular organism development 5440
          system development 5021
            nervous system development 2551
              central nervous system development 1156
                brain development 890
                  hindbrain development 210
                    metencephalon development 161
                      cerebellum development 149
                        cerebellar cortex development 64
                          cerebellar Purkinje cell layer development 34
                            cerebellar Purkinje cell layer maturation 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.