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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain-hindbrain boundary maturation
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Accession:GO:0021732 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms:related_synonym: MHB maturation;   isthmus maturation


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midbrain-hindbrain boundary maturation during brain development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 ISO MGI:MGI:1856382 (MGI:MGI:76584|PMID:8555108) RGD PMID:8555108 MGI:MGI:76584 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
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Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      developmental maturation 340
        anatomical structure maturation 286
          midbrain-hindbrain boundary maturation 1
            midbrain-hindbrain boundary maturation during brain development 1
            midbrain-hindbrain boundary maturation during neural plate development 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          embryo development 1307
            embryo development ending in birth or egg hatching 860
              chordate embryonic development 844
                neural tube development 196
                  neural tube patterning 49
                    rostrocaudal neural tube patterning 14
                      midbrain-hindbrain boundary development 9
                        midbrain-hindbrain boundary maturation 1
                          midbrain-hindbrain boundary maturation during brain development 1
                          midbrain-hindbrain boundary maturation during neural plate development 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.