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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway involved in ventral spinal cord interneuron specification
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Accession:GO:0021775 term browser browse the term
Definition:The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
Synonyms:exact_synonym: hedgehog signaling pathway involved in ventral spinal cord interneuron specification;   hh signaling pathway involved in ventral spinal cord interneuron specification;   smoothened signalling pathway involved in ventral spinal cord interneuron specification


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smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI-Kruppel family member GLI2 IGI (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr 1:118,834,061...119,054,405
Ensembl chr 1:118,834,132...119,053,619
JBrowse link
G Gli3 GLI-Kruppel family member GLI3 IGI (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chr13:15,463,723...15,730,026
Ensembl chr13:15,463,235...15,730,026
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling IMP (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chr19:46,396,896...46,488,804
Ensembl chr19:46,396,896...46,488,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23387
    developmental process 7031
      cellular developmental process 4667
        cell fate specification 102
          cell fate specification involved in pattern specification 8
            ventral spinal cord interneuron specification 8
              smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
Path 2
Term Annotations click to browse term
  biological_process 23387
    developmental process 7031
      anatomical structure development 6505
        multicellular organism development 5969
          system development 5380
            nervous system development 2722
              neurogenesis 1939
                generation of neurons 1785
                  neuron differentiation 1618
                    central nervous system neuron differentiation 245
                      ventral spinal cord interneuron differentiation 14
                        ventral spinal cord interneuron fate commitment 12
                          ventral spinal cord interneuron specification 8
                            smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
paths to the root