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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway involved in ventral spinal cord interneuron specification
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Accession:GO:0021775 term browser browse the term
Definition:The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
Comment:This term was added by GO_REF:0000021.
Synonyms:exact_synonym: hedgehog signaling pathway involved in ventral spinal cord interneuron specification;   hh signaling pathway involved in ventral spinal cord interneuron specification;   smoothened signalling pathway involved in ventral spinal cord interneuron specification


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smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      cellular developmental process 4428
        cell fate specification 104
          cell fate specification involved in pattern specification 12
            ventral spinal cord interneuron specification 12
              smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
Path 2
Term Annotations click to browse term
  biological_process 19317
    developmental process 6647
      anatomical structure development 6113
        multicellular organism development 5583
          system development 5101
            nervous system development 2597
              neurogenesis 1882
                generation of neurons 1747
                  neuron differentiation 1574
                    central nervous system neuron differentiation 238
                      ventral spinal cord interneuron differentiation 18
                        ventral spinal cord interneuron fate commitment 16
                          ventral spinal cord interneuron specification 12
                            smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.