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ONTOLOGY REPORT - ANNOTATIONS


Term:forebrain generation of neurons
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Accession:GO:0021872 term browser browse the term
Definition:The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.
Comment:This term was added by GO_REF:0000021.
Synonyms:exact_synonym: generation of neurons in forebrain


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forebrain generation of neurons term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 JBrowse link 20 47,286,843 47,306,318 RGD:1624291
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slit1 slit guidance ligand 1 JBrowse link 1 260,843,481 260,992,366 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
G Slit3 slit guidance ligand 3 JBrowse link 10 19,924,200 20,517,918 RGD:1624291
chemorepulsion involved in postnatal olfactory bulb interneuron migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1600115
RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1600115
RGD:1624291
commitment of neuronal cell to specific neuron type in forebrain term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
G Fezf2 Fez family zinc finger 2 JBrowse link 15 12,825,333 12,831,496 RGD:1624291
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Satb2 SATB homeobox 2 JBrowse link 9 63,456,877 63,642,193 RGD:1624291
G Tbr1 T-box brain transcription factor 1 JBrowse link 3 47,677,720 47,685,902 RGD:1624291
RGD:13792537
embryonic olfactory bulb interneuron precursor migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arx aristaless related homeobox JBrowse link X 62,363,757 62,376,139 RGD:1624291
RGD:1600115
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:1624291
forebrain neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspm assembly factor for spindle microtubules JBrowse link 13 56,546,021 56,591,793 RGD:1624291
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:13792537
RGD:1600115
forebrain neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2289424
G Gbx2 gastrulation brain homeobox 2 JBrowse link 9 97,063,265 97,065,855 RGD:1624291
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1624291
RGD:1600115
G Lhx6 LIM homeobox 6 JBrowse link 3 15,409,349 15,433,504 RGD:1624291
RGD:13792537
G Lhx8 LIM homeobox 8 JBrowse link 2 260,572,205 260,598,744 RGD:1624291
RGD:13792537
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Sox1 SRY-box transcription factor 1 RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:2314144
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:1624291
RGD:1600115
G Dlx1 distal-less homeobox 1 JBrowse link 3 58,164,931 58,169,521 RGD:1624291
G Dlx2 distal-less homeobox 2 JBrowse link 3 58,180,088 58,181,971 RGD:1624291
G Lhx5 LIM homeobox 5 JBrowse link 12 41,663,000 41,671,437 RGD:1624291
G Lhx8 LIM homeobox 8 JBrowse link 2 260,572,205 260,598,744 RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
G Otp orthopedia homeobox JBrowse link 2 24,546,393 24,554,953 RGD:1624291
G Phlda1 pleckstrin homology-like domain, family A, member 1 JBrowse link 7 54,247,460 54,249,664 RGD:70034
G Pou3f4 POU class 3 homeobox 4 JBrowse link X 82,143,789 82,145,066 RGD:1624291
G Sox1 SRY-box transcription factor 1 RGD:1624291
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
forebrain neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhx6 LIM homeobox 6 JBrowse link 3 15,409,349 15,433,504 RGD:1624291
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
forebrain radial glial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:8554692
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:8554692
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:13792537
RGD:1600115
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Mettl14 methyltransferase like 14 JBrowse link 2 227,566,811 227,583,047 RGD:1624291
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
gonadotrophin-releasing hormone neuronal migration to the hypothalamus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
hypothalamus gonadotrophin-releasing hormone neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ubb ubiquitin B JBrowse link 10 48,880,231 48,881,896 RGD:1624291
motogenic signaling involved in postnatal olfactory bulb interneuron migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:2325172
negative regulation of forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:8554692
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:8554692
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043320
neuroblast division in subventricular zone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akna AT-hook transcription factor JBrowse link 5 79,184,087 79,232,370 RGD:1624291
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1600115
RGD:1624291
G Numbl NUMB-like, endocytic adaptor protein JBrowse link 1 84,067,841 84,091,659 RGD:1600115
RGD:1624291
olfactory bulb interneuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf5 activating transcription factor 5 JBrowse link 1 100,807,821 100,812,410 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
G Robo2 roundabout guidance receptor 2 JBrowse link 11 11,062,866 12,618,793 RGD:1624291
G Sall3 spalt-like transcription factor 3 JBrowse link 18 77,572,200 77,591,710 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1600115
RGD:1624291
olfactory bulb interneuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf5 activating transcription factor 5 JBrowse link 1 100,807,821 100,812,410 RGD:1624291
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Dlx5 distal-less homeobox 5 JBrowse link 4 32,387,741 32,392,085 RGD:1624291
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Gsx2 GS homeobox 2 JBrowse link 14 35,650,985 35,652,709 RGD:1624291
G Mir200a microRNA 200a JBrowse link 5 173,489,366 173,489,454 RGD:1624291
G Mir200b microRNA 200b JBrowse link 5 173,490,144 173,490,238 RGD:1624291
G Mir200c microRNA 200c JBrowse link 4 157,236,786 157,236,854 RGD:1624291
G Mir3597-1 microRNA 3597-1 JBrowse link 2 187,582,790 187,582,897 RGD:1624291
G Mir9-3 microRNA 9-3 JBrowse link 1 141,229,353 141,229,442 RGD:1624291
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
G Uncx UNC homeobox JBrowse link 12 17,182,158 17,186,679 RGD:1624291
RGD:1600115
positive regulation of forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
pyramidal neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Dclk2 doublecortin-like kinase 2 JBrowse link 2 186,116,624 186,245,937 RGD:1624291
G Dcx doublecortin JBrowse link X 115,098,675 115,175,515 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Ogdh oxoglutarate dehydrogenase JBrowse link 14 86,414,924 86,481,903 RGD:1624291
G Plxna3 plexin A3 JBrowse link X 156,363,400 156,379,433 RGD:1624291
G Slc4a10 solute carrier family 4 member 10 JBrowse link 3 47,995,812 48,287,897 RGD:1624291
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII JBrowse link 10 38,779,132 38,782,489 RGD:1624291
pyramidal neuron migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:5509783
G Foxg1 forkhead box G1 JBrowse link 6 69,971,227 69,974,037 RGD:1624291
regulation of forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlx1 distal-less homeobox 1 JBrowse link 3 58,164,931 58,169,521 RGD:1624291
RGD:1600115
G Dlx2 distal-less homeobox 2 JBrowse link 3 58,180,088 58,181,971 RGD:1624291
RGD:1600115
G Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 JBrowse link 7 2,875,898 2,905,463 RGD:1624291
striatal medium spiny neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
G Inhba inhibin subunit beta A JBrowse link 17 51,894,869 51,919,998 RGD:1624291
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1624291
RGD:1600115
G Zswim6 zinc finger, SWIM-type containing 6 JBrowse link 2 38,978,042 39,042,886 RGD:1624291
ventricular zone neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1600115
RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
Wnt signaling pathway involved in forebrain neuroblast division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    developmental process 6638
      anatomical structure development 6107
        forebrain development 507
          forebrain generation of neurons 84
            forebrain neuroblast differentiation + 0
            forebrain neuroblast division + 10
            forebrain neuron differentiation + 71
            forebrain radial glial cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 19334
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            nervous system development 2602
              central nervous system development 1184
                brain development 905
                  forebrain development 507
                    forebrain generation of neurons 84
                      forebrain neuroblast differentiation + 0
                      forebrain neuroblast division + 10
                      forebrain neuron differentiation + 71
                      forebrain radial glial cell differentiation + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.