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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway involved in ventral spinal cord patterning
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Accession:GO:0021910 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.
Comment:This term was added by GO_REF:0000021.
Synonyms:exact_synonym: hedgehog signaling pathway involved in ventral spinal cord patterning;   hh signaling pathway involved in ventral spinal cord patterning;   smoothened signalling pathway in ventral spinal cord patterning


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smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1600115
RGD:1624291
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ift122 intraflagellar transport 122 JBrowse link 4 147,756,574 147,826,983 RGD:1624291
RGD:1600115
G Rfx4 regulatory factor X4 JBrowse link 7 25,831,358 25,909,976 RGD:1624291
RGD:13792537
G Rfx8 RFX family member 8, lacking RFX DNA binding domain JBrowse link 9 46,414,407 46,476,076 RGD:13792537
G Tulp3 TUB like protein 3 JBrowse link 4 161,636,084 161,677,807 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    signaling 7122
      signal transduction 6611
        cell surface receptor signaling pathway 2540
          smoothened signaling pathway 155
            smoothened signaling pathway involved in ventral spinal cord patterning 8
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 4
              smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
              smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
Path 2
Term Annotations click to browse term
  biological_process 18179
    developmental process 6551
      anatomical structure development 6031
        multicellular organism development 5511
          system development 5062
            nervous system development 2590
              central nervous system development 1177
                spinal cord development 143
                  spinal cord patterning 28
                    spinal cord dorsal/ventral patterning 26
                      smoothened signaling pathway involved in ventral spinal cord patterning 8
                        negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 4
                        smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
                        smoothened signaling pathway involved in ventral spinal cord interneuron specification 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.