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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
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Accession:GO:0021914 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.
Synonyms:exact_synonym: down regulation of smoothened signaling pathway in ventral spinal cord patterning;   downregulation of smoothened signaling pathway in ventral spinal cord patterning;   negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning;   negative regulation of hh signaling pathway involved in ventral spinal cord patterning;   negative regulation of smoothened signalling pathway in ventral spinal cord patterning
 narrow_synonym: inhibition of smoothened signaling pathway in ventral spinal cord patterning


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negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ift122 intraflagellar transport 122 ISO (MGI:4888042|PMID:21209331) RGD PMID:21209331 MGI:4888042 NCBI chr 4:147,756,574...147,826,983
Ensembl chr 4:147,756,553...147,826,997
JBrowse link
G Rfx4 regulatory factor X4 IBA
ISO
PMID:21873635
MGI:3799278 (MGI:5430880|PMID:19887680)
RGD PMID:19887680, PMID:21873635 MGI:5430880, RGD:13792537 NCBI chr 7:25,831,358...25,909,976
Ensembl chr 7:25,808,419...25,907,849
JBrowse link
G Tulp3 TUB like protein 3 ISO MGI:2388066 (MGI:3841503|PMID:19286674) RGD PMID:19286674 MGI:3841503 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      negative regulation of signaling 1374
        negative regulation of signal transduction 1236
          negative regulation of smoothened signaling pathway 38
            negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            nervous system development 2719
              central nervous system development 1260
                spinal cord development 141
                  spinal cord patterning 23
                    spinal cord dorsal/ventral patterning 21
                      smoothened signaling pathway involved in ventral spinal cord patterning 7
                        negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.