ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
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Accession:GO:0021938 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.
Comment:This term was added by GO_REF:0000021.
Synonyms:exact_synonym: hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation;   hh signaling pathway involved in regulation of granule cell precursor cell proliferation;   smoothened signalling pathway in regulation of granule cell precursor cell proliferation


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smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
RGD:1600115
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    signaling 7019
      cell-cell signaling 1598
        cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 6
          smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 4
Path 2
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        multicellular organism development 5440
          system development 5021
            nervous system development 2551
              central nervous system development 1156
                brain development 890
                  hindbrain development 210
                    cell proliferation in hindbrain 19
                      cell proliferation in external granule layer 18
                        cerebellar granule cell precursor proliferation 18
                          regulation of cerebellar granule cell precursor proliferation 13
                            positive regulation of cerebellar granule cell precursor proliferation 10
                              cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 6
                                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.