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ONTOLOGY REPORT - ANNOTATIONS


Term:central nervous system projection neuron axonogenesis
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Accession:GO:0021952 term browser browse the term
Definition:Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
Synonyms:narrow_synonym: central nervous system axon tract development


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central nervous system projection neuron axonogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family, member e22 ISO MGI:2684610|MGI:4440742|MGI:4440744 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:1926253|MGI:2158714 (MGI:2181503|PMID:11344259), (MGI:2683795|PMID:14687550), (MGI:3527366|PMID:15608630) RGD PMID:11344259, PMID:14687550, PMID:15608630 MGI:2181503, MGI:2683795, MGI:3527366 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Dclk1 doublecortin-like kinase 1 ISO MGI:1277171 (MGI:3614628|PMID:16387638) RGD PMID:16387638 MGI:3614628 NCBI chr 2:144,646,255...144,939,389
Ensembl chr 2:144,646,308...144,936,927
JBrowse link
G Dcx doublecortin IEA
ISO
GO_REF:0000107
MGI:1330861 (MGI:3614628|PMID:16387638)
Ensembl
RGD
PMID:16387638 GO_REF:0000107, MGI:3614628 NCBI chr  X:115,098,675...115,175,515
Ensembl chr  X:115,098,675...115,175,299
JBrowse link
G Ephb1 Eph receptor B1 ISS
ISO
GO_REF:0000024
MGI:2677305|MGI:2677312 (MGI:2675767|PMID:12971893)
UniProt
RGD
PMID:12971893 GO_REF:0000024, MGI:2675767 NCBI chr 8:110,376,954...110,813,193
Ensembl chr 8:110,376,954...110,813,000
JBrowse link
G Ephb2 Eph receptor B2 IBA
ISO
PMID:21873635
(MGI:2675767|PMID:12971893)
RGD PMID:12971893, PMID:21873635 MGI:2675767, RGD:13792537 NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456
JBrowse link
G Ephb3 Eph receptor B3 ISO (MGI:2675767|PMID:12971893) RGD PMID:12971893 MGI:2675767 NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
JBrowse link
G Ephb6 Eph receptor B6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:70,903,253...70,918,514
Ensembl chr 4:70,903,253...70,918,514
JBrowse link
G Mycbp2 MYC binding protein 2 ISO MGI:3777464|MGI:3777465 (MGI:3759703|PMID:17901218), (MGI:3776727|PMID:18031680) RGD PMID:17901218, PMID:18031680 MGI:3759703, MGI:3776727 NCBI chr15:87,405,472...87,450,812
NCBI chr15:93,678,062...93,901,556
Ensembl chr15:87,506,959...93,868,301
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IEA
ISO
GO_REF:0000107
MGI:2157566 (MGI:1350702|PMID:10585298)
Ensembl
RGD
PMID:10585298 GO_REF:0000107, MGI:1350702 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Prdm8 PR/SET domain 8 ISO MGI:5315763 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr14:13,052,776...13,073,583
Ensembl chr14:13,054,771...13,058,172
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 ISO MGI:3710201 (MGI:3708238|PMID:17197442) RGD PMID:17197442 MGI:3708238 NCBI chr 1:84,168,494...84,254,679
Ensembl chr 1:84,168,495...84,254,645
JBrowse link
anterior commissure morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family, member e22 ISO MGI:4440742 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Fbxo45 F-box protein 45 IEA
ISO
GO_REF:0000107
MGI:3849742 (MGI:3849342|PMID:19398581)
Ensembl
RGD
PMID:19398581 GO_REF:0000107, MGI:3849342 NCBI chr11:71,795,977...71,811,858
Ensembl chr11:71,796,282...71,808,498
JBrowse link
G Nfib nuclear factor I/B ISS
ISO
GO_REF:0000024
(MGI:4453290|PMID:19961580)
UniProt
RGD
PMID:19961580 GO_REF:0000024, MGI:4453290 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 ISO MGI:2176490 (MGI:2151063|PMID:11997145) RGD PMID:11997145 MGI:2151063 NCBI chr20:47,286,843...47,306,318
Ensembl chr20:47,288,137...47,306,318
JBrowse link
G Plxna4 plexin A4 ISO MGI:3578655 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan IEA
ISO
GO_REF:0000107
MGI:4867728 (MGI:4848234|PMID:21055390)
Ensembl
RGD
PMID:21055390 GO_REF:0000107, MGI:4848234 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
corpus callosum morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family, member e22 ISO MGI:2684610|MGI:4440742|MGI:4440744 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Grcc10 gene rich cluster, C10 gene ISO (PMID:23453665), (PMID:23453666), (PMID:23633300), (PMID:24798461) RGD PMID:23453665, PMID:23453666, PMID:23633300, PMID:24798461 NCBI chr 4:157,264,383...157,266,042
Ensembl chr 4:157,264,383...157,266,018
JBrowse link
G Nin ninein ISO MGI:1344407 (MGI:5629993|PMID:25741725) RGD PMID:25741725 MGI:5629993 NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 ISO (PMID:9063735) RGD PMID:9063735 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
G Prdm8 PR/SET domain 8 ISO MGI:5315763 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr14:13,052,776...13,073,583
Ensembl chr14:13,054,771...13,058,172
JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex ISO (PMID:23932106) RGD PMID:23932106 NCBI chr 5:137,192,120...137,238,384
Ensembl chr 5:137,190,875...137,238,354
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan IEA
ISO
GO_REF:0000107
MGI:4867728 (MGI:4848234|PMID:21055390)
Ensembl
RGD
PMID:21055390 GO_REF:0000107, MGI:4848234 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO MGI:2387499|MGI:2668659 (MGI:5629993|PMID:25741725) RGD PMID:25741725 MGI:5629993 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
corticospinal neuron axon guidance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1b sodium voltage-gated channel beta subunit 1 ISO MGI:3043422 (MGI:3778100|PMID:18354028) RGD PMID:18354028 MGI:3778100 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
corticospinal neuron axon guidance through spinal cord term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 ISO
IEA
(PMID:10975526)
GO_REF:0000107
RGD
Ensembl
PMID:10975526 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
corticospinal tract morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family, member e22 ISO MGI:2684610|MGI:4440742|MGI:4440744|MGI:99217 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Cdh11 cadherin 11 ISO MGI:1930001 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Epha4 Eph receptor A4 ISS
ISO
GO_REF:0000024
(MGI:1306963|PMID:9789074)
UniProt
RGD
PMID:9789074 GO_REF:0000024, MGI:1306963 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Fbxo45 F-box protein 45 IEA
ISO
GO_REF:0000107
MGI:3849742 (MGI:3849342|PMID:19398581)
Ensembl
RGD
PMID:19398581 GO_REF:0000107, MGI:3849342 NCBI chr11:71,795,977...71,811,858
Ensembl chr11:71,796,282...71,808,498
JBrowse link
G Nin ninein ISO MGI:1344407 (MGI:5629993|PMID:25741725) RGD PMID:25741725 MGI:5629993 NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
JBrowse link
G Prdm8 PR/SET domain 8 ISO MGI:5315763 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr14:13,052,776...13,073,583
Ensembl chr14:13,054,771...13,058,172
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO MGI:2387499|MGI:2668659 (MGI:5629993|PMID:25741725) RGD PMID:25741725 MGI:5629993 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
spinal cord ventral commissure morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adarb1 adenosine deaminase, RNA-specific, B1 IEA
ISO
GO_REF:0000107
MGI:4840554 (MGI:4831065|PMID:20826656)
Ensembl
RGD
PMID:20826656 GO_REF:0000107, MGI:4831065 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Dcc DCC netrin 1 receptor IEA
ISO
GO_REF:0000107
MGI:1934924 (MGI:87114|PMID:9126737)
Ensembl
RGD
PMID:9126737 GO_REF:0000107, MGI:87114 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Gli2 GLI family zinc finger 2 ISO MGI:1857509 (MGI:1340208|PMID:10409510) RGD PMID:10409510 MGI:1340208 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        cell development 2442
          neuron development 1323
            central nervous system neuron development 101
              central nervous system neuron axonogenesis 42
                central nervous system projection neuron axonogenesis 29
                  anterior commissure morphogenesis 6
                  corpus callosum morphogenesis 8
                  corticospinal tract morphogenesis + 9
                  cuneatus tract morphogenesis 0
                  gracilis tract morphogenesis 0
                  medulla reticulospinal tract morphogenesis 0
                  pons reticulospinal tract morphogenesis 0
                  posterior commissure morphogenesis 0
                  rubrospinal tract morphogenesis 0
                  spinal cord ventral commissure morphogenesis 3
                  spinothalamic tract morphogenesis 0
                  tectobulbar tract morphogenesis 0
                  tectospinal tract morphogenesis 0
                  trigeminothalamic tract morphogenesis 0
                  vestibulospinal tract morphogenesis 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            nervous system development 2719
              neurogenesis 1936
                generation of neurons 1780
                  neuron differentiation 1614
                    neuron development 1323
                      neuron projection development 1164
                        neuron projection morphogenesis 722
                          axonogenesis 496
                            central nervous system neuron axonogenesis 42
                              central nervous system projection neuron axonogenesis 29
                                anterior commissure morphogenesis 6
                                corpus callosum morphogenesis 8
                                corticospinal tract morphogenesis + 9
                                cuneatus tract morphogenesis 0
                                gracilis tract morphogenesis 0
                                medulla reticulospinal tract morphogenesis 0
                                pons reticulospinal tract morphogenesis 0
                                posterior commissure morphogenesis 0
                                rubrospinal tract morphogenesis 0
                                spinal cord ventral commissure morphogenesis 3
                                spinothalamic tract morphogenesis 0
                                tectobulbar tract morphogenesis 0
                                tectospinal tract morphogenesis 0
                                trigeminothalamic tract morphogenesis 0
                                vestibulospinal tract morphogenesis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.