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ONTOLOGY REPORT - ANNOTATIONS


Term:central nervous system projection neuron axonogenesis
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Accession:GO:0021952 term browser browse the term
Definition:Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
Synonyms:narrow_synonym: central nervous system axon tract development


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central nervous system projection neuron axonogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family member e22 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936496:9,085,894...9,087,623 JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:2181503|PMID:11344259), (MGI:2683795|PMID:14687550)
(MGI:3527366|PMID:15608630)
MGI PMID:11344259, PMID:14687550, PMID:15608630 MGI:2181503, MGI:2683795, MGI:3527366 NCBI chrNW_004936580:4,165,255...4,179,285 JBrowse link
G Dclk1 doublecortin like kinase 1 ISO (MGI:3614628|PMID:16387638) MGI PMID:16387638 MGI:3614628 NCBI chrNW_004936472:29,958,716...30,287,798 JBrowse link
G Dcx doublecortin ISO (MGI:3614628|PMID:16387638) MGI PMID:16387638 MGI:3614628 NCBI chrNW_004936499:3,905,262...4,004,457 JBrowse link
G Ephb1 EPH receptor B1 ISO (MGI:2675767|PMID:12971893) MGI PMID:12971893 MGI:2675767 NCBI chrNW_004936529:8,006,780...8,261,923 JBrowse link
G Ephb2 EPH receptor B2 ISO (MGI:2675767|PMID:12971893) MGI PMID:12971893 MGI:2675767 NCBI chrNW_004936474:8,109,800...8,203,106 JBrowse link
G Ephb3 EPH receptor B3 ISO (MGI:2675767|PMID:12971893) MGI PMID:12971893 MGI:2675767 NCBI chrNW_004936578:5,286,580...5,297,369 JBrowse link
G Mycbp2 MYC binding protein 2 ISO (MGI:3759703|PMID:17901218)
(MGI:3776727|PMID:18031680)
UniProt
MGI
PMID:17901218, PMID:18031680 MGI:3759703, MGI:3776727 NCBI chrNW_004936511:3,977,950...4,248,959 JBrowse link
G Nr4a2 nuclear receptor subfamily 4 group A member 2 ISO (MGI:1350702|PMID:10585298) MGI PMID:10585298 MGI:1350702 NCBI chrNW_004936469:21,912,118...21,920,486 JBrowse link
G Prdm8 PR/SET domain 8 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936749:1,819,491...1,827,440 JBrowse link
G Sptbn4 spectrin beta, non-erythrocytic 4 ISO (MGI:3708238|PMID:17197442) MGI PMID:17197442 MGI:3708238 NCBI chrNW_004936661:2,831,132...2,903,619 JBrowse link
anterior commissure morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family member e22 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936496:9,085,894...9,087,623 JBrowse link
G Fbxo45 F-box protein 45 ISO (MGI:3849342|PMID:19398581) MGI PMID:19398581 MGI:3849342 NCBI chrNW_004936784:1,162,950...1,177,407 JBrowse link
G Nfib nuclear factor I B ISO (MGI:4453290|PMID:19961580) UniProt PMID:19961580 MGI:4453290 NCBI chrNW_004936539:7,763,036...8,185,001 JBrowse link
G Nr2e1 nuclear receptor subfamily 2 group E member 1 ISO (MGI:2151063|PMID:11997145) MGI PMID:11997145 MGI:2151063 NCBI chrNW_004936564:4,432,556...4,453,056 JBrowse link
G Plxna4 plexin A4 ISO (MGI:3578029|PMID:15814794) MGI PMID:15814794 MGI:3578029 NCBI chrNW_004936579:3,025,251...3,449,347 JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan ISO (MGI:4848234|PMID:21055390) MGI PMID:21055390 MGI:4848234 NCBI chrNW_004936498:5,434,912...5,487,354 JBrowse link
corpus callosum morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family member e22 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936496:9,085,894...9,087,623 JBrowse link
G CUNH12orf57 chromosome unknown C12orf57 homolog ISO (PMID:23453665), (PMID:23453666), (PMID:23633300), (PMID:24798461) UniProtKB PMID:23453665, PMID:23453666, PMID:23633300, PMID:24798461 NCBI chrNW_004936709:884,741...886,617 JBrowse link
G Nin ninein ISO (MGI:5629993|PMID:25741725) MGI PMID:25741725 MGI:5629993 NCBI chrNW_004936495:14,791,246...14,897,454 JBrowse link
G Pafah1b1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 ISO (PMID:9063735) BHF-UCL PMID:9063735 NCBI chrNW_004936538:8,612,142...8,693,698 JBrowse link
G Prdm8 PR/SET domain 8 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936749:1,819,491...1,827,440 JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex ISO (PMID:23932106) UniProtKB PMID:23932106 NCBI chrNW_004936474:24,788,175...24,837,471 JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan ISO (MGI:4848234|PMID:21055390) MGI PMID:21055390 MGI:4848234 NCBI chrNW_004936498:5,434,912...5,487,354 JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO (MGI:5629993|PMID:25741725) MGI PMID:25741725 MGI:5629993 NCBI chrNW_004936469:32,240,730...32,372,413 JBrowse link
corticospinal neuron axon guidance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1b sodium voltage-gated channel beta subunit 1 ISO (MGI:3778100|PMID:18354028) MGI PMID:18354028 MGI:3778100 NCBI chrNW_004936570:1,187,916...1,195,423 JBrowse link
corticospinal neuron axon guidance through spinal cord term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 ISO (PMID:10975526) BHF-UCL PMID:10975526 NCBI chrNW_004936477:8,111,212...8,448,567 JBrowse link
corticospinal tract morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family member e22 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936496:9,085,894...9,087,623 JBrowse link
G Cdh11 cadherin 11 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936475:15,513,402...15,662,330 JBrowse link
G Epha4 EPH receptor A4 ISO (MGI:1306963|PMID:9789074) UniProt PMID:9789074 MGI:1306963 NCBI chrNW_004936569:3,539,269...3,670,322 JBrowse link
G Fbxo45 F-box protein 45 ISO (MGI:3849342|PMID:19398581) MGI PMID:19398581 MGI:3849342 NCBI chrNW_004936784:1,162,950...1,177,407 JBrowse link
G Nin ninein ISO (MGI:5629993|PMID:25741725) MGI PMID:25741725 MGI:5629993 NCBI chrNW_004936495:14,791,246...14,897,454 JBrowse link
G Prdm8 PR/SET domain 8 ISO (MGI:5315201|PMID:22284184) MGI PMID:22284184 MGI:5315201 NCBI chrNW_004936749:1,819,491...1,827,440 JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO (MGI:5629993|PMID:25741725) MGI PMID:25741725 MGI:5629993 NCBI chrNW_004936469:32,240,730...32,372,413 JBrowse link
spinal cord ventral commissure morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adarb1 adenosine deaminase RNA specific B1 ISO (MGI:4831065|PMID:20826656) MGI PMID:20826656 MGI:4831065 NCBI chrNW_004936778:1,056,259...1,137,772 JBrowse link
G Dcc DCC netrin 1 receptor ISO (MGI:87114|PMID:9126737) MGI PMID:9126737 MGI:87114 NCBI chrNW_004936497:10,122,078...11,169,900 JBrowse link
G Gli2 GLI family zinc finger 2 ISO (MGI:1340208|PMID:10409510) MGI PMID:10409510 MGI:1340208 NCBI chrNW_004936469:49,616,552...49,788,760 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    developmental process 5648
      anatomical structure development 5286
        cell development 2116
          neuron development 1160
            central nervous system neuron development 95
              central nervous system neuron axonogenesis 41
                central nervous system projection neuron axonogenesis 28
                  anterior commissure morphogenesis 6
                  corpus callosum morphogenesis 8
                  corticospinal tract morphogenesis + 9
                  cuneatus tract morphogenesis 0
                  gracilis tract morphogenesis 0
                  medulla reticulospinal tract morphogenesis 0
                  pons reticulospinal tract morphogenesis 0
                  posterior commissure morphogenesis 0
                  rubrospinal tract morphogenesis 0
                  spinal cord ventral commissure morphogenesis 3
                  spinothalamic tract morphogenesis 0
                  tectobulbar tract morphogenesis 0
                  tectospinal tract morphogenesis 0
                  trigeminothalamic tract morphogenesis 0
                  vestibulospinal tract morphogenesis 0
Path 2
Term Annotations click to browse term
  biological_process 12002
    developmental process 5648
      anatomical structure development 5286
        multicellular organism development 4845
          system development 4567
            nervous system development 2365
              neurogenesis 1700
                generation of neurons 1563
                  neuron differentiation 1412
                    neuron development 1160
                      neuron projection development 1027
                        neuron projection morphogenesis 609
                          axonogenesis 398
                            central nervous system neuron axonogenesis 41
                              central nervous system projection neuron axonogenesis 28
                                anterior commissure morphogenesis 6
                                corpus callosum morphogenesis 8
                                corticospinal tract morphogenesis + 9
                                cuneatus tract morphogenesis 0
                                gracilis tract morphogenesis 0
                                medulla reticulospinal tract morphogenesis 0
                                pons reticulospinal tract morphogenesis 0
                                posterior commissure morphogenesis 0
                                rubrospinal tract morphogenesis 0
                                spinal cord ventral commissure morphogenesis 3
                                spinothalamic tract morphogenesis 0
                                tectobulbar tract morphogenesis 0
                                tectospinal tract morphogenesis 0
                                trigeminothalamic tract morphogenesis 0
                                vestibulospinal tract morphogenesis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.